|Related Categories||A to C, Bioactive Small Molecules, Biochemicals and Reagents, Calcineurin, Cell Biology,|
|solubility||DMSO: soluble20 mg/mL|
|Gene Information||human ... FKBP1A(2280)|
FK-506 is a potent immunosuppressant, neuroprotective and neuroregenerative, and in vitro T cell proliferation blocker. FK-506 disrupts calcineurin-mediated signal transduction in T lymphocytes and interacts with its FK-506-binding protein-12 (FKBP12).
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from Tolypocladium inflatum, ≥95% (HPLC), solid
from Tolypocladium inflatum, BioReagent, for molecular biology, ≥95%
Ready Made Solution, 2.5 mg/mL in DMSO (2.74 mM), from Streptomyces hygroscopicus
Certificate of Analysis
Certificate of Origin
|Precautionary statements||P301 + P310|
|Personal Protective Equipment||Eyeshields, Faceshields, Gloves, type P2 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T|
|Risk Statements (Europe)||25|
|Safety Statements (Europe)||45|
|RIDADR||UN 2811 6.1 / PGIII|
Phosphoprotein phosphatases, which hydrolyze the phosphoester bonds of phosphoserines, phosphothreonines or phosphotyrosines, play an essential role in signal transduction and actively contribute to ...
Keywords: Catalysis, Cloning, Gene expression, Neurotransmitters, Phosphorylations, Transduction
Reversible Cyclosporin A-sensitive Mitochondrial Depolarization Occurs Within Minutes Of Stroke Onset In Mouse Somatosensory Cortex In Vivo: A Two-photon Imaging Study. Liu, R.R., and Murphy, T.H. J. Thorac. Cardiovasc. Surg. 284, 36109-17, (2009)
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