|Related Categories||Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, F,|
Class IC antiarrhythmic agent; sodium channel blocker
Certificate of Analysis
Certificate of Origin
Potassium channels are essential in both excitable and non-excitable cells for the control of membrane potential, regulation of cell volume, and the secretion of salt, neurotransmitters and hormones....
Keywords: Absorption, Cancer, Cell proliferation, Cell signaling, Diabetes, Diseases, Hormones, Ligands, Neurotransmitters, Phosphorylations, Sequencing
Voltage-gated sodium channels are present in most excitable cell membranes and play an important role in generating action potentials. A variety of toxins and chemicals are known to either block or m...
Keywords: Analgesics, Atomic absorption spectroscopy, Central Nervous System, Gene expression, Insecticides, Neurotoxins
Hypertonic sodium bicarbonate versus intravenous lipid emulsion in a rabbit model of intravenous flecainide toxicity: no difference, no sink. Cave G, Harvey M, Quinn P, et al. Clin. Toxicol. (Phila.) 51(5), 394-7, (2013)
Comparison of the intrinsic vasorelaxant and inotropic effects of the antiarrhythmic agents vernakalant and flecainide in human isolated vascular and cardiac tissues. Lynch JJ, Regan CP, Beatch GN, et al. J. Cardiovasc. Pharmacol. 61(3), 226-32, (2013)
A novel, potent, and selective inhibitor of cardiac late sodium current suppresses experimental arrhythmias. Belardinelli L, Liu G, Smith-Maxwell C, et al. J. Pharmacol. Exp. Ther. 344(1), 23-32, (2013)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?