|Related Categories||Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies to Cell and Organelle Proteins, Antibodies to ER and Golgi Proteins,|
|species reactivity||human, rabbit, hamster, canine, monkey, bovine, rat, kangaroo rat, chicken, goose|
|indirect immunofluorescence: 1:20 using cultured Chinese hamster ovary (CHO) cells|
|antibody form||ascites fluid|
|contains||15 mM sodium azide|
|shipped in||dry ice|
human ... COPB1(1315)|
rat ... Copb1(114023)
microtubule-associated protein from goose brain.
The antibody recognizes an epitope shared by β-COP (110 kDa) found in most tissue culture lines, and by a doublet of brain microtubule-associated protein (MAP2, 270-300 kDa). The antibody stains a reticular structure in the perinuclear area of non-neuronal cells (the periphery of Golgi complex and a population of coatomers scattered throughout the cytoplasm) in tissues from different species and cell processes, as well as cell bodies in chicken brain neuronal cells. It has been used for studies on the effects of various agents that influence energy status, disrupt the Golgi complex, or alter the activity of G-proteins or small GTP-binding proteins on the cellular localization of β-COP.1 The antibody may be used for the immunoaffinity purification of the protein.2
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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