Monoclonal Anti-Interleukin-1β antibody produced in mouse
clone 8516.311, purified immunoglobulin, lyophilized powder
DOWNLOAD MSDS (PDF)Synonym: Anti-IL-1β
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MDL number MFCD00162514
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Popular Documents: Datasheet (PDF) | Specification Sheet (PDF)
Properties
| Related Categories | 8, Alphabetical Index, Antibodies, Antibodies against Cytokines, Chemokines, and Growth Factors for Stem Cell Biology, Antibodies against Cytokines/Growth Factors/Chemokines for Stem Cell Biology, |
| species reactivity | human |
| application(s) | flow cytometry: suitable |
| immunohistochemistry: 8-25 μg/mL using human PBMC′s | |
| neutralization: suitable | |
| western blot: 1 μg/mL | |
| clone | 8516.311, monoclonal |
| antibody form | purified immunoglobulin |
| form | lyophilized powder |
| isotype | IgG1 |
| storage temp. | −20°C |
| Gene Information | human ... IL1B(3553) |
Description
Immunogen
purifed, E. coli-derived, recombinant human IL-1β.
Physical form
Lyophilized from a 0.2 μm filtered solution in phosphate buffered saline pH 7.4 with 5% trehalose.
Specificity
The antibody will neutralize the biological activity of recombinant human IL-1β. It will not neutralize the activity of recombinant human IL-α, recombinant mouse IL-1α, or recombinant mouse IL-1β. When immobilized on a microplate, this antibody will capture both recombinant as well as natural human IL-1β. In immunoblotting, the antibody shows ~25% cross-reactivity with recombinant rat IL-1β and <5% cross-reactivity with recombinant mouse IL-1β and recombinant porcine IL-1β. Additionally, in immunoblotting, the antibody exhibits no cross-reactivity with recombinant mouse IL-α, recombinant human IL-1ra, recombinant mouse IL-1ra, or recombinant rat IL-1α.
Preparation Note
Monoclonal Anti-Interleukin-1(IL-1
Application
May used in immunoblotting, immunohistochemistry, ELISA, and neutralization assays
Price and Availability
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