|Related Categories||Androgen Modulators, Antitumor Agents, Bioactive Small Molecules, Cancer Research, Cell Biology,|
human ... GNRHR(2798)|
rat ... Gnrhr(81668)
Luteinizing hormone releasing hormone (LH-RH) agonist.
Gonadotropin-releasing hormone agonist has the ability to induce increased matrix metalloproteinase (MMP)-2 and membrane type 1-MMP expression in corpora lutea, and structural luteolysis in rats. Goto, T., et al. J. Endocrinol. 161, 393-402, (1999)
Design, synthesis, and structure-activity relationships of thieno[2,3-b]pyridin-4-one derivatives as a novel class of potent, orally active, non-peptide luteinizing hormone-releasing hormone receptor antagonists. Takashi Imada et al J. Med. Chem. 49, 3809-25, (2006)
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