L4385 Sigma

α-Lactalbumin from bovine milk

Marker for non-denaturing PAGE

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Properties

Related Categories Biochemicals and Reagents, Milk Proteins, Proteins and Derivatives More...
form   lyophilized powder
mol wt   mol wt ~14.2 kDa
storage temp.   −20°C
Gene Information   cow ... LALBA(281894)

Description

Reconstitution

0.9-1.4 mg/mL after reconstitution with 1 mL of water

Biochem/physiol Actions

Alters the substrate specificity of galactosyltransferase to increase the rate of lactose formation; the complex of galactosyltransferase and α-lactalbumin is called lactose synthase. Site-directed mutagenesis of Asp87 or Asp88 to Ala completely abolishes the strong calcium binding affinity and reduces the stimulation of lactose synthase to <3.5% of the maximal rate.1

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