L6004 Sigma

Lincomycin hydrochloride

≥90% (TLC)

DOWNLOAD MSDS (PDF)

Synonym: Lincocin hydrochloride, Methyl 6,8-dideoxy-6-(1-methyl-4-propyl-2-pyrrolidinecarboxamido)-1-thio-D-erythro-α-D-galactooctopyranoside hydrochloride

  • CAS Number 859-18-7

  • Empirical Formula (Hill Notation) C18H34N2O6S · HCl

  • Molecular Weight 443.00

  •  Beilstein Registry Number 4171650

  •  EC Number 212-726-7

  •  MDL number MFCD00083647

  • Popular Documents:  Specification Sheet (PDF)  

Properties

Related Categories Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics G-M, Chemical Structure Class,
assay   ≥90% (TLC)
potency   800-900 units per mg
storage temp.   2-8°C

Description

Biochem/physiol Actions

Lincomycin is a lincosamide antibiotic that forms cross-links within the peptidyl transferase loop region of the 23S rRNA.3
Mode of action: inhibits bacterial protein synthesis
Antimicrobial spectrum: Gram-positive bacteria

Application

Lincomycin hydrochloride is an antibiotic used to study the inhibition of protein synthesis, bacterial antibiotic resistance, and protein and surfactant binding 1,2 Product L6004 is ≥90% (TLC). It is produced by Streptomyces lincolnensis var. lincolnensis and has been used in the treatment of Staphylococcal, Streptococcal, and Bacteroides fragilis infections.

Protocols & Applications

Antibiotic Selector for application, solubility, solution stability, working concentration, and mode of action information

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