L9664 Sigma

Loratadine

≥98% (HPLC), powder

DOWNLOAD MSDS (PDF)

Synonym: 4-(8-Chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene-1-piperidinecarboxylic acid ethyl ester, Loratidine

  • CAS Number 79794-75-5

  • Empirical Formula (Hill Notation) C22H23N2O2Cl

  • Molecular Weight 382.88

  •  MDL number MFCD00672869

  •  PubChem Substance ID 24278525

Properties

Related Categories Antagonists, Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Biochemicals and Reagents, Cell Biology,
assay   ≥98% (HPLC)
form   powder
color   white
solubility   DMSO: soluble50 mg/mL
  H2O: insoluble
storage temp.   2-8°C
Gene Information   human ... CYP3A4(1576), HRH1(3269), KCNH1(3756), KCNH2(3757), PTAFR(5724)
rat ... Hrh1(24448)

Description

Biochem/physiol Actions

Non-sedating histamine H1-receptor antagonist.

Other Notes

Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. L9664.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.

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