M5324
Sigma
PX 12
≥98% (HPLC), powder
DOWNLOAD MSDS (PDF)Synonym:
2-
-
CAS Number 141400-58-0
-
Empirical Formula (Hill Notation) C7H12N2S2
-
Molecular Weight 188.31
-
MDL number MFCD18086851
Properties
| Related Categories | Aerobic Glycolysis (the Warburg Effect), Cancer Metabolism, Cancer Research, Cell Biology, Cell Signaling and Neuroscience, |
| assay | ≥98% (HPLC) |
| form | powder |
| color | off-white to tan |
| solubility | DMSO: >25 mg/mL |
| storage temp. | 2-8°C |
Description
Biochem/physiol Actions
PX-12 inhibits the thioredoxin redox system and HIF-1a activity. PX 12 inhibits hypoxia-induced HIF-1a transcriptional activity (IC50 11 nM) and proliferation of HT29 and MCF-7 tumor cells (IC50 1.9 and 0.9 uM, respectively).
Price and Availability
Customers Also Viewed
C9623Chetomin
from Chaetomium cochliodes, ≥98% (HPLC)
Technical Service:
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Bulk Ordering & Pricing:
Need larger quantities for your development, manufacturing or research applications?
