|Related Categories||Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Multi-Drug Resistance, Antibodies to Drug Efflux Pumps,|
|application(s)||immunocytochemistry: 1:20-1:50 using acetone-fixed cytospin preparations|
|immunohistochemistry (frozen sections): 1:20 using acetone-fixed frozen sections|
|western blot: 1:20-1:50|
|antibody form||tissue culture supernatant|
|mol wt||antigen mol wt 190-200 kDa|
|shipped in||dry ice|
|Gene Information||human ... ABCC5(10057)|
human MRP5 (amino acids 82-168) bacterial fusion protein.
Supplied in serum-free culture medium containing 0.7% bovine serum albulin and 0.1% sodium azide.
Reacts with an internal epitope of MRP5. Does not cross-react with the human MDR1, MRP1, MRP2, MRP3 gene products.
Chemotherapy is the treatment of choice against many types of cancer. However, over time chemotherapeutic drugs can become less effective due to the development of resistance that involves a group of...
BioFiles 2007, 2.4, 7.
Keywords: Absorption, Cancer, Clinical, Cloning, Combinatorial synthesis, Diseases, Enzymology, Gene expression, Genetic, Immunology, Pharmaceutical, Reductions, Transfection
As a leading supplier of antibodies, Sigma® Life Science is committed to providing researchers the antibody they need with the quality they deserve. Our Antibody Explorer Search Tool provides easy ac...
Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
Analysis of expression of cMOAT (MRP2), MRP3, MRP4, and MRP5 homologs of the multidrug resistance-associated protein gene (MRP1), in human cancer cell lines. Kool, M., et al. Cancer Res. 57, 3537-3547, (1997)
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