Monoamine Oxidase B human
recombinant, expressed in baculovirus infected BTI insect cells
DOWNLOAD MSDS (PDF)Synonym: MAO-B
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EC Number 231-791-2
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MDL number MFCD04040933
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Popular Documents: Datasheet (PDF) | Specification Sheet (PDF)
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Properties
| Related Categories | 1.4.x.x Acting on CH-NH2, 1.x.x.x Oxidoreductases, Analytical and Industrial Enzymes, Biochemicals and Reagents, Cell Biology, |
| recombinant | expressed in baculovirus infected BTI insect cells |
| assay | ~2.5 mg per vial |
| shipped in | dry ice |
| storage temp. | −70°C |
| Gene Information | human ... MAOB(4129) |
Description
Biochem/physiol Actions
MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.
General description
Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs. 2
Application
Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression. 1
Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.
Price and Availability
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≥0.05 unit/mg solid
recombinant, expressed in wild-type baculovirus infected BTI insect cells
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