|Related Categories||1.4.x.x Acting on CH-NH2, 1.x.x.x Oxidoreductases, Analytical and Industrial Enzymes, Biochemicals and Reagents, Cell Biology,|
|recombinant||expressed in baculovirus infected BTI insect cells|
|assay||~2.5 mg per vial|
|shipped in||dry ice|
|Gene Information||human ... MAOB(4129)|
MAO′s are proteins of the mitochondrial membrane. These enzymes are responsible for catalyzing oxidative deamination of endo- and xenobiotic amines. Substrate specificity differs for each isozyme.
Monoamine Oxidase B is a mitochondrial outermembrane flavoenzyme that is a target for antidepressant and neuroprotective drugs. 2
Drugs that inhibit monoamine oxidase B activity are used for the treatment of various neurological disorders including depression. 1
Monoamine Oxidase B has been used in a study to assess the effect of age in 23 different regions of the human brain. It has also been used in a study to determine the specific locations of monoamine oxidase in the human brain.
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≥0.05 unit/mg solid
recombinant, expressed in baculovirus infected BTI insect cells
recombinant, expressed in wild-type baculovirus infected BTI insect cells
powder, ≥98% (HPLC)
Certificate of Analysis
Certificate of Origin
|Personal Protective Equipment||Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)|
2. Structure of human monoamine oxidase B, a drug target for the treatment of neurological disorders Binda, C., et al. Nat. Struct. Biol. 9, 22-6, (2001)
Interactions of nitrogencontaining xenobiotics with monoamine oxidase (MAO) isozymes A and B: SAR studies on MAO substrates and inhibitors. Kalgutkar, A.S., et al. Chem. Res. Toxicol. 14, 1139-1162, (2001)
The effect of age on the activity and molecular properties of human brain monoamine oxidase Fowler, C., et al. J. Neural Transm. Gen. Sect. 49, 1-20, (1980)
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|M7566||Monoamine Oxidase Insect Cell Control, recombinant, expressed in wild-type baculovirus infected BTI insect cells|
|M7316||Monoamine Oxidase A human, recombinant, expressed in baculovirus infected BTI insect cells|
|M1821||Anti-Monoamine Oxidase B antibody produced in rabbit, ~1.5 mg/mL, affinity isolated antibody, buffered aqueous solution|
|M1946||Anti-Monoamine Oxidase B (C-terminal) antibody produced in rabbit, affinity isolated antibody, ~1.5 mg/mL, buffered aqueous solution|
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