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N0258 Sigma

N-Nitrosodiethylamine

ISOPAC®

Synonym: Diethylnitrosamine

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Properties

Related Categories Cancer Research, Carcinogens, Cell Biology More...
bp   177 °C(lit.)
density   0.95 g/mL(lit.)

Description

Frequently Asked Questions

Frequently Asked Questions are available for this Product.

Biochem/physiol Actions

Carcinogenic in all animal species tested. The main target organs are the nasal cavity, trachea, lung, esophagus and liver.

Caution

Injecting any compatible solvent permits preparation of any desired strength solution without exposure.

Packaging

1 g in serum bottle

Packaged in a 100 mL serum bottle with silicon/PTFE septum and aluminum tear seal.

Reconstitution

Dissolving the contents in 100 mL of solvent yields a 1% solution.

Legal Information

Isopac is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 2810 6.1/PG 3
WGK Germany 
3
RTECS 
IA3500000
Protocols & Articles

Articles

Carcinogenesis and Epigenetics

Cancer research has revealed that the classical model of carcinogenesis, a three step process consisting of initiation, promotion, and progression, is not complete. The expansion of the carcinogenesi...
Vicki Caligur
BioFiles 2008, 3.5, 18.
Keywords: Acetylations, Adhesion, Alkylations, Apoptosis, Biofiles, Cancer, Carcinogens, Cell division, Cell proliferation, Cell signaling, DNA microarrays, Drug discovery, Environmental, Epigenetics, Events, Gene expression, Genetic, Hormones, Metabolism, Methylations, Microarray Analysis, Mutagens, PAGE, Recombination, Reductions, Sequences, Transcription, Type, transformation

DNA Damage and Repair

Damage to cellular DNA is involved in mutagenesis and the development of cancer. The DNA in a human cell undergoes several thousand to a million damaging events per day, generated by both external (e...
Keywords: AGE, Alkylations, Apoptosis, Cancer, Carcinogens, Catalysis, Clinical, DNA replication, Deaminations, Environmental, Gene expression, Metabolites, Methylations, Mutagens, Oxidations, Polymorphisms, Rearrangements, Recombination, Substitutions, Transcription

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Peer-Reviewed Papers
15

References

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N0756 N-Nitrosodiethylamine, liquid

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