|Related Categories||Biochemicals and Reagents, NAD(P)(H) Analogs, NAD(P)(H) and Analogs, Nucleosides, Nucleotides, Oligonucleotides|
|mp||291-293 °C (dec.)(lit.)|
Nicotinamide N-oxide is a niacin-related compound used in studies of mechanisms of niacin-related granulocyte differentiation of cells such as human promyelocytic leukemia cells (HL-60). Nicotinamide N-oxide reduced expression of c-myc in HL-60 cell line.
Tandem Mass Spectrometry data independently generated by Scripps Center for Metabolomics is available to view or download in PDF. N3258.pdf Tested metabolites are featured on Scripps Center for Metabolomics METLIN Metabolite Database. To learn more, visit sigma.com/metlin.
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|Precautionary statements||P261-P305 + P351 + P338|
|Personal Protective Equipment||dust mask type N95 (US), Eyeshields, Gloves|
|Hazard Codes (Europe)||Xi|
|Risk Statements (Europe)||36/37/38|
|Safety Statements (Europe)||26-36|
Changes in the gene expression of C-myc and CD38 in HL-60 cells during differentiation induced by nicotinic acid-related compounds. Ida C, Ogata S, Okumura K, Taguchi H. Biosci. Biotechnol. Biochem. 72, 868-871, (2008)
Spectroscopic (NMR, UV, FT-IR and FT-Raman) analysis and theoretical investigation of nicotinamide N-oxide with density functional theory. Atac A, Karabacak M, Kose E, Karaca C. Spectrochim. Acta A 83(1), 250-258, (2011)
Aldrich MSDS 1, 1348:D / Corp MSDS 1 (2), 2540:D / FT-IR 1 (2), 917:A / FT-IR 2 (3), 3998:A / IR-Spectra (2), 1240:A / IR-Spectra (3), 1423:A / NMR-Reference 2 (2), 777:D / RegBook 1 (2), 2681:M / Sigma FT-IR 1 (2), 772:D / Structure Index 1, 421:E:7
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