Pediocin from Pediococcus acidilactici
≥95% (HPLC), buffered aqueous solution
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CAS Number 133108-87-9
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Properties
| Related Categories | Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class, |
| assay | ≥95% (HPLC) |
| form | buffered aqueous solution |
| concentration | 0.1 mg/mL in 0.1 M sodium acetate pH 5.0 |
| shipped in | dry ice |
| storage temp. | −20°C |
Description
Biochem/physiol Actions
Pediocins are class IIa bacteriocins that are produced by Pediococcus sp.3 They are cationic peptides that show strong activity against pathogenic bacteria such as Listeria monocytogenes, Clostridicum perfringes, Enterococcus faecalis, and Staphylococcus aureus.4 This antimicrobial action of pediocins is based on interaction with the cytoplasmic membrane, resulting in pore formation and cell death.
Pediocin′s antimicrobial activities are based on interactions with the cytoplasmic membrane which results in a change of membrane potentials. This leads to a loss of the proton motive force, an efflux of intracellular ions, and ultimately cell death1. They have been shown to inhibit Listeria monocytogenes2.
Application
Pediocins are class IIa bacteriocins that are produced by Pediococcus acidilactici. They are cationic peptides that have molecular masses of about 2,700 to 4,000 Da1. They are active against pathogenic bacteria such as Listeria monocytogenes, Clostridicum perfringes, Enterococcus faecalis, and Staphylococcus aureus. They are a potential food biopreservatives to control food-borne pathogens and spoilage1. They have been used to inhibit Listeria monocytogenes2.
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