|Related Categories||Antibacterial, Antibiotics, Antibiotics A to Z, Antibiotics N-S, Chemical Structure Class,|
|form||buffered aqueous solution|
|concentration||0.1 mg/mL in 0.1 M sodium acetate pH 5.0|
|shipped in||dry ice|
Pediocins are class IIa bacteriocins that are produced by Pediococcus sp.3 They are cationic peptides that show strong activity against pathogenic bacteria such as Listeria monocytogenes, Clostridicum perfringes, Enterococcus faecalis, and Staphylococcus aureus.4 This antimicrobial action of pediocins is based on interaction with the cytoplasmic membrane, resulting in pore formation and cell death.
Pediocin′s antimicrobial activities are based on interactions with the cytoplasmic membrane which results in a change of membrane potentials. This leads to a loss of the proton motive force, an efflux of intracellular ions, and ultimately cell death1. They have been shown to inhibit Listeria monocytogenes2.
Pediocins are class IIa bacteriocins that are produced by Pediococcus acidilactici. They are cationic peptides that have molecular masses of about 2,700 to 4,000 Da1. They are active against pathogenic bacteria such as Listeria monocytogenes, Clostridicum perfringes, Enterococcus faecalis, and Staphylococcus aureus. They are a potential food biopreservatives to control food-borne pathogens and spoilage1. They have been used to inhibit Listeria monocytogenes2.
With bacterial resistance and emerging infectious diseases becoming potential threats to humans, ribosomally synthesized antimicrobial peptides have become a promising focus area in antibiotic resear...
BioFiles 2009, 4.3, 4.
Keywords: Antibiotics, Antimicrobials, Antiparasitics, Antivirals, Apoptosis, Cancer, Clinical, Diseases, Environmental, Fermentation, Food Safety, Gene expression, Genetic, Genetics, Infectious Diseases, Microbiology, Peptide synthesis, Pesticides, Respiratory
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