Anti-Protein Kinase Cζ antibody produced in rabbit
whole antiserum
DOWNLOAD MSDS (PDF)Synonym: Anti-PKC ζ
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MDL number MFCD00162775
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Popular Documents: Datasheet (PDF)
Properties
| Related Categories | Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies in Array, |
| species reactivity | mouse, rat |
| application(s) | microarray: suitable |
| western blot: suitable using rat brain extract and mouse NIH3T3 fibroblast cell lysate | |
| clone | polyclonal |
| antibody form | whole antiserum |
| mol wt | antigen mol wt 78 kDa |
| contains | 15 mM sodium azide |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information |
mouse ... Prkcz(18762) rat ... Prkcz(25522) |
Description
Immunogen
Synthetic peptide corresponding to the C-terminal variable (V5) region (amino acids 577-592) of PKC ζ coupled to KLH.
General description
Protein Kinase C (PKC) is a 76-93 kD phospholipid-dependent enzyme that belongs to serine/threonine protein kinases family. It has a pivotal role in cell growth and differentiation, modulation of neurotransmission, signal transduction and oncogenesis1. PKC ζ isoform is expressed mainly in many cells and tissues2 and is activated by cis- unsaturated fatty acids. Anti-protein kinase C ζ antibody can be used for studying differential tissue expression and intracellular localization of PKC ζ. It can also be used for studying PKC expression in normal and neoplastic tissues. Rabbit anti-protein kinase C ζ antibody reacts specifically with PKC ζ (78 kD) from rat brain extract. The product is also specific for PKC ζ (78-80 kD proteins appearing as doublet) from NIH 3T3 mouse fibroblasts lysate.
Application
Anti-protein kinase C ζ antibody can be used in immunoblot to detect PKC ζ isoenzyme by using rat brain extracts and cell culture extracts. It can also be used in microarray.
Price and Availability
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~1 mg/mL, affinity isolated antibody, buffered aqueous solution
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