Phenylmethanesulfonyl fluoride

Papers

1. Phenylmethylsulfonyl fluoride (PMSF) given systemically produces naloxone-reversible analgesia and potentiates effects of beta-endorphin given centrally Pinsky, C., et al. Life Sci. 31, 1193-1196, (1982)

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Kinetic analysis of differences in brain acetylcholinesterase from fish or mammalian sources. Moss, D.E. and Fahrney, D.E. Biochem. Pharmacol. 27, 2693, (1978)

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The action of phenylmethylsulfonyl fluoride on human acetylcholinesterase, chymotyrpsin and trypsin. Turini, P., et al. J. Pharmacol. Exp. Ther. 167, 98, (1969)

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Inactivation of the protease inhibitor phenylmethylsulfonyl fluoride in buffers. James, G.T. Anal. Biochem. 86, 574, (1978)

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Maintaining protein stability. Deutscher, M.P Meth. Enzymol. 182, 83-89, (1990)

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Preparation of extracts from yeast. Jazwinski, S.M Meth. Enzymol. 182, 154, (1990)

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Preparation of extracts from plants. Gegenheimer, P. Meth. Enzymol. 182, 174-193, (1990)

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Preparation of extracts from higher eukaryotes. Dignam, J.D Meth. Enzymol. 182, 194-203, (1990)

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Identifying catalytic residues in CPAF, a Chlamydia-secreted protease. Chen, D., et al. Arch. Biochem. Biophys. 485, 16-23, (2009)

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Largamides A-C, tiglic acid-containing cyclodepsipeptides with elastase-inhibitory activity from the marine cyanobacterium Lyngbya confervoides. Matthew, S., et al. Planta Med. 75, 528-33, (2009)

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Role Of Nonspecific Cytotoxic Cells In Bacterial Resistance: Expression Of A Novel Pattern Recognition Receptor With Antimicrobial Activity. Connor, M.A., et al. Mol. Hum. Reprod. 46, 953-61, (2009)

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Mechanism Of Interferon-gamma Mediated Down-regulation Of Interleukin-10 Gene Expression. Schaefer, A., et al. Mol. Immunol. 46, 1351-9, (2009)

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Sex-related Resistance To Myocardial Ischemia-reperfusion Injury Is Associated With High Constitutive ARC Expression. Bouma, W., et al. Am. J. Physiol. Heart Circ. Physiol. 298, H1510-7, (2010)

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TDP-43 Is A Transcriptional Repressor: THE TESTIS-SPECIFIC MOUSE Acrv1 GENE IS A TDP-43 TARGET IN VIVO. Lalmansingh, A.S., et al. J. Thorac. Cardiovasc. Surg. 286, 10970-82, (2011)

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Caspase Inhibition Blocks Cell Death And Enhances Mitophagy But Fails To Promote T-cell Lymphoma. Wang, S.H., et al. PLoS ONE 6, e19786, (2011)

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Peptides released from reovirus outer capsid form membrane pores that recruit virus particles. Tijana Ivanovic et al EMBO J. 27, 1289-98, (2008)

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Isolation of neuronal chromatin from brain tissue. Yan Jiang et al BMC Neurosci. 9, 42, (2008)

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Interleukin (IL)-6 modulates transforming growth factor-β expression in skin and dermal fibroblasts from IL-6-deficient mice. L.R. Luckett-Chastain et al Br. J. Dermatol. 161, 237-48, (2009)

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Chronic exposure to arsenic in the drinking water alters the expression of immune response genes in mouse lung. Courtney D. Kozul et al Environ. Health Perspect. 117, 1108-15, (2009)

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The endocannabinoid system: drug targets, lead compounds, and potential therapeutic applications. Didier M Lambert et al J. Med. Chem. 48, 5059-87, (2005)

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Profiling the enzymatic properties and inhibition of human complement factor B. Giang Thanh Le et al J. Biol. Chem. 282, 34809-16, (2007)

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The evaluation and structure-activity relationships of 2-benzoylaminobenzoic esters and their analogues as anti-inflammatory and anti-platelet aggregation agents. Pei-Wen Hsieh et al Bioorg. Med. Chem. Lett. 17, 1812-7, (2007)

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Discovery and development of fatty acid amide hydrolase (FAAH) inhibitors. Mark Seierstad et al J. Med. Chem. 51, 7327-43, (2008)

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Phthalides from Pittosporum illicioides var. illicioides with inhibitory activity on superoxide generation and elastase release by neutrophils. Tsung-Hsien Chou et al J. Nat. Prod. 71, 1692-5, (2008)

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Neolignans, a coumarinolignan, lignan derivatives, and a chromene: anti-inflammatory constituents from Zanthoxylum avicennae. Jih-Jung Chen et al J. Nat. Prod. 71, 212-7, (2008)

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Benzoic acid derivatives, acetophenones, and anti-inflammatory constituents from Melicope semecarpifolia. Jih-Jung Chen et al J. Nat. Prod. 71, 71-5, (2008)

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Design and synthesis of new N-(fluorenyl-9-methoxycarbonyl) (Fmoc)-dipeptides as anti-inflammatory agents. Chiao-Ting Yen et al Eur. J. Med. Chem. 44, 1933-40, (2009)

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Amides and benzenoids from Zanthoxylum ailanthoides with inhibitory activity on superoxide generation and elastase release by neutrophils. Jih-Jung Chen et al J. Nat. Prod. 72, 107-11, (2009)

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Anti-inflammatory flavonoids from the rhizomes of Helminthostachys zeylanica. Yaun-Chao Huang et al J. Nat. Prod. 72, 1273-8, (2009)

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Benzophenone derivatives from the fruits of Garcinia multiflora and their anti-inflammatory activity. Jih-Jung Chen et al J. Nat. Prod. 72, 253-8, (2009)

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Antitumor agents. 271: total synthesis and evaluation of brazilein and analogs as anti-inflammatory and cytotoxic agents. Chiao-Ting Yen et al Bioorg. Med. Chem. Lett. 20, 1037-9, (2010)

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Ixorapeptide I and ixorapeptide II, bioactive peptides isolated from Ixora coccinea. Chia-Lin Lee et al Bioorg. Med. Chem. Lett. 20, 7354-7, (2010)

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Synthesis and evaluation of benzoxazinone derivatives on activity of human neutrophil elastase and on hemorrhagic shock-induced lung injury in rats. Pei-Wen Hsieh et al Eur. J. Med. Chem. 45, 3111-5, (2010)

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Action of a pentacyclic triterpenoid, maslinic acid, against Toxoplasma gondii. Luis M De Pablos et al J. Nat. Prod. 73, 831-4, (2010)

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Synthesis and biological evaluation of novel irreversible serine protease inhibitors using amino acid based sulfonyl fluorides as an electrophilic trap. Arwin J Brouwer et al Bioorg. Med. Chem. 19, 2397-406, (2011)

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Inhibitory effects of Mannich bases of heterocyclic chalcones on NO production by activated RAW 264.7 macrophages and superoxide anion generation and elastase release by activated human neutrophils. M Vijaya Bhaskar Reddy et al Bioorg. Med. Chem. 19, 2751-6, (2011)

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Bioactive constituents from the roots of Panax japonicus var. major and development of a LC-MS/MS method for distinguishing between natural and artifactual compounds. Hsiu-Hui Chan et al J. Nat. Prod. 74, 796-802, (2011)

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Sequestration of mutated alpha1-antitrypsin into inclusion bodies is a cell-protective mechanism to maintain endoplasmic reticulum function. Granell S Mol. Biol. Cell 19(2), 572-86, (2008)

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Multiple protonation states of vesicular acetylcholine transporter detected by binding of [3H]vesamicol. Khare P Biochemistry 48(38), 8965-75, (2009)

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Beynon, R.J. and Bond, J.S., ed. Proteolytic Enzymes: A Practical Approach New York, NY , (1989), 246

Merck 14,7542

Beil. 11,III,331