Penicillin G sodium salt
~1650 U/mg
DOWNLOAD MSDS (PDF)Synonym: Benzylpenicillin sodium salt
-
CAS Number 69-57-8
-
Empirical Formula (Hill Notation) C16H17N2NaO4S
-
Molecular Weight 356.37
-
Beilstein Registry Number 3834217
-
EC Number 200-710-2
-
MDL number MFCD00069666
-
PubChem Substance ID 24899068
Properties
| Related Categories | Antibiotics, Antibiotics A to Z, Antibiotics N-S, Apoptosis and Cell Cycle, Cell Biology, |
Description
Biochem/physiol Actions
Mode of Action: Inhibits bacterial cell wall synthesis.
Antimicrobial spectrum: Gram-positive bacteria.
Penicillin G is active against gram-positive and gram-negative aerobic and anaerobic bacteria. Penicillin G inhibits cell wall synthesis by binding to penicillin binding proteins (PBPs), which inhibits peptidoglycan chain cross-linking. Penicillin G is stable against hydrolysis by β-lactamases, such as penicillinases and cephalosporinases.
Application
Penicillin G is narrow spectrum antibiotic. It is the drug of choice for Streptococcus pneumoniae, groups A, B, C and G streptococci, nonenterococcal group D streptococci, viridans group streptococci, and non-penicillinase producing staphylococcus. Penicillin G sodium salt is used to study the diagnostic and therapeutic implications of gentamicin-resistant Enterococcus faecalis sequence type 6 with reduced penicillin susceptibility 1. It is used in cell culture alone as well as in combination with streptomcyin and other antibiotics2.
Protocols & Applications
Price and Availability
Customers Also Viewed
Solution stabilized, with 10,000 units penicillin and 10 mg streptomycin/mL, sterile-filtered, BioReagent, suitable for cell culture
Technical Service:
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Bulk Ordering & Pricing:
Need larger quantities for your development, manufacturing or research applications?
