|Related Categories||Approved Therapeutics/Drug Candidates, Arachidonic Acid Cascade, Cell Biology, Cell Signaling and Neuroscience, Cyclooxygenase,|
|color||white to off-white|
|solubility||DMSO: >25 mg/mL|
|storage temp.||room temp|
Valdecoxib is a non-steroidal anti-inflammatory drug (NSAID), a cyclooxygenase-2 (COX-2) selective inhibitor.
Sold for research purposes under agreement from Pfizer Inc.
It is well established that the brain can sense and react to peripheral insults through the rapid induction of fever and other neuroendocrine changes in response to events such as infection and tissu...
Scott Hauser, Technology Transfer Specialist, Sigma® Life Science
Biofiles, Vol. 8, No. 19
Keywords: Adhesion, Biofiles, Central Nervous System, Diseases, Events, Gene expression, Inflammation, Neurodegenerative Diseases, Reductions, Type
Targeting oxidative stress, mitochondrial dysfunction and neuroinflammatory signaling by selective cyclooxygenase (COX)-2 inhibitors mitigates MPTP-induced neurotoxicity in mice. Gupta, a., et al. Prog. Neuropsychopharmacol. Biol. Psychiatry Jan 31th ed.,, (2011)
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