Rutin hydrate
≥94% (HPLC), powder
DOWNLOAD MSDS (PDF)Synonym:
Quercetin-
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CAS Number 207671-50-9
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Empirical Formula (Hill Notation) C27H30O16 · xH2O
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Molecular Weight 610.52 (anhydrous basis)
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Beilstein Registry Number 75455
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EC Number 205-814-1
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MDL number MFCD00149490
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PubChem Substance ID 24899379
Properties
| Related Categories | Acacia, Allium cepa (Onion), Allium sativum (Garlic), Antioxidant and Free Radical Scavengers, Antioxidants and Cytoprotectants, |
| assay | ≥94% (HPLC) |
| form | powder |
| color | yellow to green |
| mp | 195 °C (dec.)(lit.) |
| solubility | pyridine: soluble50 mg/mL |
| DMSO: soluble | |
| aqueous base: soluble |
Description
Biochem/physiol Actions
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodimethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
Protocols & Applications
Ginkgo (Ginkgo biloba) Plant Profile: bioactives, mechanism of action, references
Price and Availability
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≥95% (HPLC), solid
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