|Related Categories||Acacia, Allium cepa (Onion), Allium sativum (Garlic), Antioxidant and Free Radical Scavengers, Antioxidants and Cytoprotectants,|
|color||yellow to green|
|mp||195 °C (dec.)(lit.)|
|solubility||pyridine: soluble50 mg/mL|
|aqueous base: soluble|
A polyphenolic flavonoid that acts as an antioxidant and NO scavenger. It can attenuate peroxide production in glial cells by acting as a free radical scavenger and protect renal cells from oxidative injury. Inclusion of rutin in the diet of rats significantly reduced the appearance of single-strand breaks in nuclear DNA caused by hepatocarcinogens aflatoxin B1 and N-nitrosodimethylamine. This protection from DNA damage was found to be due to a reduction in the induction of repair enzymes polymerase, DNA polymerase β and DNA ligase. Since DNA damage and inefficient repair are thought to initiate the process of carcinogenesis, effects of rutin on these functions suggests a protective role of this flavonoid against carcinogenesis induced by chemical carcinogens.
Certificate of Analysis
Certificate of Origin
Corp MSDS 1 (2), 3061:D / FT-IR 1 (2), 96:D / FT-IR 2 (2), 2510:D / IR-Spectra (2), 793:F / IR-Spectra (3), 906:H / RegBook 1 (2), 1699:C / Sax 6, 2377 / Sigma FT-IR 1 (1), 710:B
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