|Related Categories||Cell Culture, Classic Media and Salts, RPMI- 1640 Medium More...|
|suitability||suitable for cell culture|
RPMI 1640 Medium was developed at Roswell Park Memorial Institute in 1966 by Moore and his co-workers. A modification of McCoy′s 5A Medium, it was formulated to support lymphoblastoid cells in suspension culture, but it has since been shown to support a wide variety of cells that are anchorage dependent. Originally intended to be used with a serum supplement, RPMI 1640 has been shown to support several cell lines in the absence of serum. It has also been widely used in fusion protocols and in the growth of hybrid cells.
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HEPES Modification, With 25 mM HEPES, without
with 2.05 mM
With sodium bicarbonate, without
HEPES Modification, with
RPMI-1640 was developed by Moore et. al. at Roswell Park Memorial Institute, hence the acronym RPMI. The formulation is based on the RPMI-1630 series of media utilizing a bicarbonate buffering system...
Keywords: Cell culture, Metabolism, Vitamins
In infertile women, cells from Chlamydia trachomatis infected sites release higher levels of interferon-gamma, interleukin-10 and tumor necrosis factor-alpha upon heat-shock-protein stimulation than fertile women. Srivastava P Reprod. Biol. Endocrinol. 6, 20, (2008)
Leishmania donovani infection down-regulates TLR2-stimulated IL-12p40 and activates IL-10 in cells of macrophage/monocytic lineage by modulating MAPK pathways through a contact-dependent mechanism. Chandra D Clin. Exp. Immunol. 154(2), 224-34, (2008)
A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus. Willger SD PLoS Pathog. 4(11), e1000200, (2008)
Immunization with oligomannose-coated liposome-entrapped dense granule protein 7 protects dams and offspring from Neospora caninum infection in mice. Nishikawa Y Clin. Vaccine Immunol. 16(6), 792-7, (2009)
Safety and Immunogenicity of a Human Papillomavirus Peptide Vaccine (CIGB-228) in Women with High-Grade Cervical Intraepithelial Neoplasia: First-in-Human, Proof-of-Concept Trial. Solares AM, Baladron I, Ramos T, et al. ISRN Obstet. Gynecol. 2011, 292951, (2011)
Low-dose priming before vaccination with the phase I chloroform-methanol residue vaccine against Q fever enhances humoral and cellular immune responses to Coxiella burnetii. David M. Waag et al Clin. Vaccine Immunol. 15, 1505-12, (2008)
Comparison of assessment of oxygen consumption, Etest, and CLSI M38-A2 broth microdilution methods for evaluation of the susceptibility of Aspergillus fumigatus to posaconazole. Ricardo Araujo et al Antimicrob. Agents Chemother. 53, 4921-3, (2009)
Leea indica Ethyl Acetate Fraction Induces Growth-Inhibitory Effect in Various Cancer Cell Lines and Apoptosis in Ca Ski Human Cervical Epidermoid Carcinoma Cells. Wong Yau Hsiung et al Evid. Based. Complement. Alternat. Med. 2011, 293060, (2011)
Polysaccharides from Agaricus bisporus and Agaricus brasiliensis show similarities in their structures and their immunomodulatory effects on human monocytic THP-1 cells. Smiderle FR BMC Complement Altern. Med. 11, 58, (2011)
Peptidoglycan from lactobacilli inhibits interleukin-12 production by macrophages induced by Lactobacillus casei through Toll-like receptor 2-dependent and independent mechanisms. Shida K Immunology 128(1 Suppl), e858-69, (2009)
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