Antibodies against Proteins/Bioactives/Marke|
|species reactivity||mouse, rat, human|
|application(s)||immunocytochemistry: 10 μg/mL using A431 cells|
|immunoprecipitation: 4 μg using STAT3 from 0.5–1 mg of an EGF stimulated human A431 cell lysate|
|western blot (chemiluminescent): 0.5-2 μg/mL using lysates from EGF stimulated human A431, mouse WEHI and rat L6 cells|
|antibody form||IgG fraction of antiserum|
|form||buffered aqueous solution|
|mol wt||antigen mol wt 92 kDa|
|shipped in||dry ice|
human ... STAT3(6774)|
mouse ... Stat3(20848)
rat ... Stat3(25125)
GST fusion protein corresponding to amino acids 688-722 of human STAT3, expressed in bacteria.
Solution in 0.1 M Tris-glycine, pH 7.4, containing 0.15 M NaCl and 0.05% sodium azide.
The antibody is specific for STAT3. It may detect an additional 66 kDa band using high concentrations or long exposures. The sequence recognized by the antibody (688-722) is identical in mouse and rat STAT3. The first 28 amino acids are identical to mouse STAT3B.
Traditionally, cancer has been viewed as a disease in which environmental or endogenous events induce mutations to critical oncogenes and tumor suppressor genes within a normal cell. The clinical man...
BioFiles 2008, 3.5, 4.
Keywords: Angiogenesis, Apoptosis, Asymmetric synthesis, Cancer, Catalysis, Cell culture, Cell division, Cell proliferation, Clinical, DNA replication, Degradations, Eliminations, Environmental, Gastrointestinal, Gene expression, Growth factors, Ligands, Metabolic Pathways, Phosphorylations, Poisons, Transcription, Transfection, transformation
As a leading supplier of antibodies, Sigma® Life Science is committed to providing researchers the antibody they need with the quality they deserve. Our Antibody Explorer Search Tool provides easy ac...
Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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