SAB3300032 Sigma

Monoclonal Anti-NT3 antibody produced in mouse

clone 3D4, purified immunoglobulin, buffered aqueous glycerol solution

DOWNLOAD MSDS (PDF)

Synonym: Anti-HDNF, Anti-MGC129711, Anti-NGF-2

Properties

Related Categories 3C-3E, Alphabetical Index, Antibodies, Cell Biology, Clone Index,
species reactivity   human
application(s)   western blot: suitable
clone   3D4, monoclonal
antibody form   purified immunoglobulin
form   buffered aqueous glycerol solution
isotype   IgG2a
mol wt   antigen mol wt 27.4 kDa
shipped in   dry ice
storage temp.   −20°C
Gene Information   human ... NTF3(4908)
NCBI accession no.   NM_001102654

Description

Immunogen

Recombinant protein expressed in E. coli corresponding to amino acids 139-257 of human NT3

Antigen Background

NT3 is a member of the neurotrophin family, that controls survival and differentiation of mammalian neurons. It is closely related to both nerve growth factor and brain-derived neurotrophic factor. It may be involved in the maintenance of the adult nervous system, and may affect development of neurons in the embryo when it is expressed in human placenta. NT3-deficient mice generated by gene targeting display severe movement defects of the limbs. The mature peptide of this protein is identical in all mammals examined including human, pig, rat, and mouse.

Physical form

Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.

Price and Availability

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