Monoclonal Anti-Pdx1 antibody produced in mouse
clone 5D5, purified immunoglobulin, buffered aqueous glycerol solution
DOWNLOAD MSDS (PDF)Synonym: Anti-GSF, Anti-IDX-1, Anti-IDX-2, Anti-IPF1, Anti-IUF1, Anti-IUF2
Properties
| Related Categories | 5, Alphabetical Index, Antibodies, Antibodies against Proteins, Bioactives, Markers, and Receptors for Stem Cell Biology, Antibodies to Drug Transport Proteins, |
| species reactivity | human |
| application(s) | western blot: suitable |
| clone | 5D5, monoclonal |
| antibody form | purified immunoglobulin |
| form | buffered aqueous glycerol solution |
| isotype | IgG1 |
| mol wt | antigen mol wt 30.6 kDa |
| shipped in | dry ice |
| storage temp. | −20°C |
| Gene Information | human ... PDX1(3651) |
| NCBI accession no. |
NM_000209
|
Description
Immunogen
Recombinant protein expressed in E. coli corresponding to amino acids 1-283 of human Pdx1
Antigen Background
Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Physical form
Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.
Price and Availability
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