Synonym: Anti-GSF, Anti-IDX-1, Anti-IDX-2, Anti-IPF1, Anti-IUF1, Anti-IUF2
|Related Categories||5, Alphabetical Index, Antibodies, Antibodies against Proteins, Bioactives, Markers, and Receptors for Stem Cell Biology, Antibodies to Drug Transport Proteins,|
|application(s)||western blot: suitable|
|antibody form||purified immunoglobulin|
|form||buffered aqueous glycerol solution|
|mol wt||antigen mol wt 30.6 kDa|
|shipped in||dry ice|
|Gene Information||human ... PDX1(3651)|
|NCBI accession no.||NM_000209|
Recombinant protein expressed in E. coli corresponding to amino acids 1-283 of human Pdx1
Pdx1 is a transcriptional activator of several genes, including insulin, somatostatin, glucokinase, islet amyloid polypeptide, and glucose transporter type 2. It is involved in the early development of the pancreas and plays a major role in glucose-dependent regulation of insulin gene expression. Defects in PDX1 gene are a cause of pancreatic agenesis, which can lead to early-onset insulin-dependent diabetes mellitus (NIDDM), as well as maturity onset diabetes of the young type 4 (MODY4).
Solution in phosphate buffered saline containing 1% bovine serum albumin, 50% glycerol, and 0.02% sodium azide.
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Keywords: Buffers, Cell biology, Epigenetics, Immunohistochemistry, Immunoprecipitation, Molecular biology, Neuroscience, Western blot
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