SAB4300272 Sigma

Anti-phospho-PLCG2 (pTyr1217) antibody produced in rabbit

affinity isolated antibody

DOWNLOAD MSDS (PDF)

Synonym: Anti-phospholipase C, gamma 2 (phosphatidylinositol-specific) antibody produced in rabbit

Properties

Related Categories Alphabetical Index, Antibodies, Antibodies for Cell Biology, Antibodies for Kinase/Phosphatase Biology, Antibodies to Phosphoproteins at Phosphotyrosine (pTyr),
species reactivity   human, mouse, rat
application(s)   immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:50-1:100
antibody form   affinity isolated antibody
immunogen sequence   (F-L-YP-D-T)
mol wt   mol wt ~150 kDa
shipped in   wet ice
storage temp.   −20°C
Gene Information   human ... PLCG2(5336)
NCBI accession no.   NP_002652.2

Description

Immunogen

Peptide sequence around phosphorylation site of tyrosine 1217 (F-L-Y(p)-D-T), according to the protein PLCG2.

Antigen Background

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. It is a crucial enzyme in transmembrane signaling.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Price and Availability

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