SML0035 Sigma

Tiagabine hydrochloride

≥98% (HPLC)

DOWNLOAD MSDS (PDF)

Synonym: (-)-(R)-1-[4,4-bis(3-methyl-2-thienyl)-3-butenyl]nipecotic acid hydrochloride, (3R)-1-[4,4-Bis(3-methyl-2-thienyl)-3-buten-1-yl]-3-piperidinecarboxylic acid hydrochloride

  • CAS Number 145821-59-6

  • Empirical Formula (Hill Notation) C20H25NO2S2 · xHCl

  • Molecular Weight 375.55 (free base basis)

  •  MDL number MFCD07369025

Properties

Related Categories Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cephalon,
assay   ≥98% (HPLC)
form   powder
optical activity   [α]/D -8.5 to 10°, c = 1 in H2O
color   white to tan
solubility   H2O: ≥14 mg/mL
storage temp.   2-8°C

Description

Biochem/physiol Actions

Tiagabine hydrochloride is an anticonvulsant and selective GABA reuptake inhibitor through inhibition of the synaptic GABA transporter GAT1.

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