|Related Categories||Approved Therapeutics/Drug Candidates, Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Cytokines and Growth Factors,|
|color||white to tan|
|solubility||DMSO: ≥8 mg/mL|
GW788388 is a potent selective inhibitor of TGF-beta type I receptor [activin receptor-like kinase 5 (ALK5)]. GW788388 is orally available with a half-life of approximately 4 hours.
Targeted inhibition of activin receptor-like kinase 5 signaling attenuates cardiac dysfunction following myocardial infarction. Tan SM, et al. Am. J. Physiol. Heart Circ. Physiol. 298, H1415-1425, (2010)
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