CTACK (CCL27) from mouse
recombinant, expressed in E. coli, ≥98% (SDS-PAGE), ≥98% (HPLC), cell culture tested
DOWNLOAD MSDS (PDF)Synonym: ALP, CCL27, Cuteaneous T-cell Attracting Chemokine, Skinkine
Properties
| Related Categories | Cell Biology, Cell Signaling and Neuroscience, Chemokines, Cytokines and Growth Factors, Cytokines, Growth Factors and Chemokines for Stem Cell Differentiation, |
| recombinant | expressed in E. coli |
| assay | ≥98% (HPLC) |
| ≥98% (SDS-PAGE) | |
| form | lyophilized |
| mol wt | mol wt 10.9 kDa |
| impurities | endotoxin, tested |
| suitability | cell culture tested |
Description
Biochem/physiol Actions
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.
Reconstitution
Centrifuge the vial prior to opening. Reconstitute in water to a concentration of 0.1-1.0 mg/ml. Do not vortex. This solution can be stored at 2-8°C for up to 1 week. For extended storage, it is recommended to further dilute in a buffer containing a carrier protein (example 0.1% BSA) and store in working aliquots at -20°C to -80°C.
Physical form
Lyophilized with no additives.
General description
CTACK is a keratinocyte-derived CC chemokine which signals through the CCR10 receptor. Both CTACK and CCR10 are expressed in normal and irritated epithelial cells. CTACK selectively attracts CLA+ T-cells and directs them into the skin. CTACK contains the four highly conserved cysteine residues present in most CC chemokines. The mature protein contains 88 amino acid residues. Recombinant murine CTACK is a 10.9 kDa protein containing 95 amino acid residues.
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