T2452 Sigma

Talsaclidine

≥98% (HPLC), oil

DOWNLOAD MSDS (PDF)

Synonym: (R)-3-(2-Propynyloxy)-1-Azabicyclo[2.2.2]octane, WAL 2014

  • CAS Number 147025-53-4

  • Empirical Formula (Hill Notation) C10H15NO

  • Molecular Weight 165.23

Properties

Related Categories Bioactive Small Molecules, Cell Biology, Cell Signaling and Neuroscience, Neuroscience, Neurotransmission,
assay   ≥98% (HPLC)
form   oil
solubility   DMSO: >5 mg/mL
storage temp.   −20°C

Description

Packaging

Packaged under argon

Biochem/physiol Actions

Talsaclidine is a M1 selective muscarinic receptor agonist. Concentration-dependently, talsaclidine increases the release of APPs and dose-dependently. Talsaclidine decreases Aβ formation and decreases cerebrospinal fluid Aβ in AD patients.

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