|Related Categories||Analytical/Chromatography, Ascentis Express Columns for Fast HPLC, Ascentis Express Peptide ES-C18, 2.7μm HPLC Columns, HPLC, HPLC Columns, by Brand for Small Molecules,|
|limit||≤100 °C temp. range|
|L × I.D.||15 cm × 2.1 mm|
|impurities||<5 ppm metals|
|matrix||Fused-Core particle platform|
|particle size||2.7 μm|
|pore size||160 Å|
|surface area||80 m2/g|
|operating pH range||1 - 9|
|suitability||suitable for L1 per USP|
Live Chat and Frequently Asked Questions are available for this Product.
Ascentis Express Peptide ES-C18 columns are specifically engineered to separate higher molecular weight compounds such as peptides and small proteins. These columns contain advanced Fused-Core particles that have larger pores (160 Å versus 90 Å in standard Ascentis Express), bonded with sterically-protected C18 ligands to provide extra stability (ES) at very low pH (< 1) and high temperatures (up to 100ºC). This greatly expands the application range for Ascentis Express columns.
Watch a 3-minute presentation that describes the Applications and Advantages of Peptide ES-C18 Columns.
Ascentis is a registered trademark of Sigma-Aldrich Co. LLC
Peptide mapping is an established technique for assessing changes to the primary structure of a protein. This has applications in areas of quality control or fundamental research in which changes to ...
Reporter US Volume 28
Keywords: Alkylations, Chromatography, Diffusion, Digestions, High performance liquid chromatography, Liquid chromatography mass spectrometry, Mass spectrometry, Nucleic acid denaturation, Oxidations, Phase transitions, Reductions, Reversed-phase chromatography, Sample preparations
Ascentis Express C18 is the first choice for starting a new method. However, when a C18 doesn't give the desired separation or your sample contains compounds that are known to be difficult to retain ...
Keywords: High performance liquid chromatography, Separation, Supercritical fluid chromatography
Calculates conditions for transfer of an isocratic or gradient method from one HPLC column to another. Allows method scaling from microbore through preparative column range. Calculates time and solve...
Keywords: High performance liquid chromatography
Accelerating high quality bioanalytical LC/MS/MS assays using fused core columns Ethan R. Badman, Richard L. Beardsley, Zhenmin Liang, Surendra Bansal J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878, 2307-2313, (2010)
Practical comparision of 2.7 µm fused-core silica particles and porous sub-2 µm particles for fast separations in pharmaceutical process development Ahmed Abrahim, Mohammad Al-Sayah, Peter Skrdla, Yuri Bereznitski, Yadan Chen, Naijun Wu J. Pharm. Biomed. Anal. 51, 131-137, (2010)
Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.
Need larger quantities for your development, manufacturing or research applications?