EMAIL THIS PAGE TO A FRIEND
103276 Aldrich

Harmane

98%

Synonym: 1-Methyl-9H-pyrido[3,4-b]indole, 2-Methyl-β-carboline, Aribine

  • CAS Number 486-84-0

  • Empirical Formula (Hill Notation) C12H10N2

  • Molecular Weight 182.22

  •  Beilstein Registry Number 143898

  •  EC Number 207-642-2

  •  MDL number MFCD00004957

  •  PubChem Substance ID 24846602

  • Popular Documents:  FTNMR (PDF)  

Purchase

Description

Biochem/physiol Actions

I1 imidazoline binding site agonist.

Packaging

1 g in glass bottle

Preparation Note

Harmane dissolves in methanol at a concentration of 50mg/ml to form a clear, colourless to yellow solution.

Application

• Harmane was used in trace level determination of harmane by planar chromatography coupled with (tandem) mass spectrometry.
• It was used to study interactions of norharman and harman with DNA.
• It may be used as matrix for analysis of cyclodextrins and for sulfated oligosaccharides in combination with DHB as co-matrix.

General description

• Harmane is a potent tremor-producing β-carboline alkaloid and neurotoxin.
• It is major representative of heterocyclic aromatic amines, a group of mutagenic and carcinogenic substances which are formed in meat from the precursors creatine, creatinine, amino acids and sugars during the heating at high temperatures.
• Blood harmane concentration is elevated in essential tremor, late-life neurological disease.

Protocols & Applications

Methods of glycosylated protein analysis by Mass Spectrometry

Price and Availability


Amplified Detection
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
RTECS 
UV0280000
Protocols & Articles

Articles

Mass Spectrometry of Glycans

The development of modern mass spectrometry (MS) equipment with high resolution and mass accuracy has led to its use in analyzing glycans for both profiling and structural studies. Unlike the HPLC me...
Glycobiology Analysis Manual, 2nd Edition
Keywords: Applications, Catalysis, Centrifugation, High performance liquid chromatography, Mass spectrometry, Phase transitions, Proteomics, Reductions, Sample preparations, Search, Sequencing, Spectra

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?