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  • 108812 - 2-Aminobenzothiazole

108812 Aldrich



Synonym: 2-Benzothiazolamine



Related Categories Building Blocks, C3 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Thiazoles More...
assay   97%
mp   126-129 °C(lit.)
solubility   H2O: very slightly soluble
  alcohol: freely soluble
  chloroform: freely soluble
  concentrated acid: soluble
  diethyl ether: freely soluble



100 g in poly bottle

5 g in glass bottle


2-Aminobenzothiazole was used in the synthesis of cobalt(II) picrate mixed-ligand complexes1. It was used to study adsorption of biologically significant 2-aminobenzothiazole molecules on colloidal silver particles using surface-enhanced raman scattering spectroscopy2.

Biochem/physiol Actions

2-Aminobenzothiazole has local anaesthetic action and has numerous applications in human and veterinary medicine2.

General description

2-Aminobenzothiazole is a neutral carrier (ionophore) used to construct a poly (vinyl chloride)-based membrane electrode for determination of Ce3+ ions3. 2-Aminobenzothiazole bonds chemically to multiwalled carbon nanotubes to produce a sorbent which has been used for separation of Pb(II) from aqueous samples4.

Price and Availability

Suggested Laboratory Gloves

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Safety & Documentation

Safety Information

GHS07  GHS07
Signal word 
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
UN 2811 6.1 / PGIII
WGK Germany 
Protocols & Articles


Determination of Water Content in 2-Aminobenzothiazole Using Karl Fischer Titration

Nitrogen compounds, acid amides and weakly basic amines (heterocyclenes) give no problems. They can be titrated according to the standard procedures. Strongly basic amines alter the pH value and must...
Keywords: Titrations

Peer-Reviewed Papers


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1. Synthesis, magnetic and spectral studies of Co (ll) picrate complexes with heterocyclic nitrogen donors. Maurya RC and Sharma P. Indian J. Chem. 38, 509-513, (1999)

2. Adsorption of 2-aminobenzothiazole on colloidal silver particles: an experimental and theoretical surface-enhanced Raman scattering study. Sarkar J, Chowdhury J, Ghosh M, et al. J. Phys. Chem. B 109(26), 12861-7, (2005)


3. A new cerium (III)-selective membrane electrode based on 2-aminobenzothiazole. Akhond M, et al Sens. Actuators B Chem. 99(2), 410-415, (2004)

4. Multiwalled carbon nanotubes modified with 2-aminobenzothiazole modified for uniquely selective solid-phase extraction and determination of Pb (II) ion in water samples. Li R, et al. Microchim. Acta 172(3-4), 269-276, (2011)

Simultaneous determination of benzothiazoles, benzotriazoles and benzosulfonamides by solid phase microextraction-gas chromatography-triple quadrupole mass spectrometry in environmental aqueous matrices and human urine. Naccarato A, Gionfriddo E, Sindona G, et al. J. Chromatogr. A. 1338, 164-73, (2014)


Virtual screening identification of nonfolate compounds, including a CNS drug, as antiparasitic agents inhibiting pteridine reductase. S. Ferrari, et al., J. Med. Chem. 54, 211-221, (2011)


Synthesis, antioxidant properties and radioprotective effects of new benzothiazoles and thiadiazoles. Damien Cressier et al Bioorg. Med. Chem. 17, 5275-84, (2009)


Merck 14,424

Beil. 27,IV,4824

FT-IR 2 (3), 3654:A / FT-IR 1 (2), 702:C / FT-NMR 1 (3), 206:A / IR-Spectra (2), 1114:E / IR-Spectra (3), 1281:A / NMR-Reference 2 (2), 576:C / RegBook 1 (2), 2455:I / Sax 6, 199 / Sigma FT-IR 1 (2), 257:C / Structure Index 1, 388:A:8

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