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109185 Aldrich

Saccharin

≥98%

Synonym: 2,3-Dihydroxy-1,2-benzisothiazol-3-one-1,1-dioxide, 2-Sulfobenzoic acid imide, o-Benzoic sulfimide

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Properties

Related Categories Building Blocks, C3 to C7, Chemical Synthesis, Heterocyclic Building Blocks, Thiazoles More...
InChI Key   CVHZOJJKTDOEJC-UHFFFAOYSA-N
assay   ≥98%
mp   226-229 °C(lit.)
solubility   H2O: soluble 1g in 290ml
  acetone: soluble 1g in 12ml
  alcohol: soluble 1g in 31ml
  boiling water: soluble 1g in 25ml
  glycerol: soluble 1g in 50ml
  alcohol: very slightly soluble
  chloroform: slightly soluble
  diethyl ether: slightly soluble

Description

Biochem/physiol Actions

A sweet tastant for mammals. A glycerol taste receptor binding site specific for glucose has been proposed in drosophila.

Dietery administration of saccharin after N-methyl-N′-nitro-N-nitrosoguanidine promotes tumor development in rats.

Packaging

250, 500 g in poly bottle

Application

Saccharin was used in high performance liquid chromatographic method for the simultaneous separation and determination of acesulfame potassium, saccharine and aspartame. It was used in sweet preference test of rats.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
2
RTECS 
DE4200000
Protocols & Articles
Peer-Reviewed Papers
15

References

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