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112631 Aldrich

2-Methoxy-4-nitroaniline

98%

Synonym: 4-Nitro-o-anisidine

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Properties

Related Categories Amines, Building Blocks, C7, Chemical Synthesis, Nitrogen Compounds,
InChI Key   GVBHRNIWBGTNQA-UHFFFAOYSA-N
assay   98%
mp   140-142 °C(lit.)

Description

Packaging

100 g in glass bottle

Application

2-Methoxy-4-nitroaniline is used as a photometric reagent for the determination of ethinylestradiol (ETE), a semi-synthetic estrogen that is widely used in oral contraceptives.

Biochem/physiol Actions

The metabolism of 2-methoxy-4-nitroaniline (MNA) occurs via the hydroxylation of the phenyl ring to form 6-hydroxy MNA in Harlan Sprague Dawley rats and B6C3F(1)/N mice.

General description

2-Methoxy-4-nitroaniline is an important inducer of CYP1A2 owing to its small molecular size.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
RIDADR 
UN 3077 9 / PGIII
WGK Germany 
3
RTECS 
BZ7170000
Protocols & Articles
Peer-Reviewed Papers
15

References

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