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  • 11590 - 4,4′-Azobis(4-cyanovaleric acid)

11590 Aldrich

4,4′-Azobis(4-cyanovaleric acid)

≥98.0% (T)

Synonym: 4,4′-Azobis(4-cyanopentanoic acid), ABCVA, ACVA

  • CAS Number 2638-94-0

  • Linear Formula HOCOCH2CH2C(CH3)(CN)N=NC(CH3)(CN)CH2CH2COOH

  • Molecular Weight 280.28

  •  Beilstein Registry Number 1729856

  •  EC Number 220-135-0

  •  MDL number MFCD00002799

  •  PubChem Substance ID 24847250



Related Categories Azo Compounds, Azo/Diazo Compounds, Building Blocks, Chemical Synthesis, Free Radical Initiators,
assay   ≥98.0% (T)
impurities   ≤1% water
mp   118-125 °C (dec.)(lit.)
storage temp.   2-8°C



4,4′-Azobis(4-cyanovaleric acid) has been used in the preparation of polystyrene particles by polymerizing styrene in ethyl alcohol.

Biochem/physiol Actions

4,4′-azobis(4-cyanovaleric acid) is an azo-initiator that induces lipid peroxidation of sunflower oil.

Price and Availability

Suggested Laboratory Gloves

Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.

Safety & Documentation

Safety Information

GHS02  GHS02
Signal word 
Hazard statements 
UN3226 - class 4.1 - Self-reactive solid type D (4,4'-AZOBIS(4-CYANOVALERIC ACID))
WGK Germany 
Protocols & Articles


A Micro Review of Reversible Addition/Fragmentation Chain Transfer (RAFT) Polymerization

RAFT (Reversible Addition/Fragmentation Chain Transfer) polymerization is a reversible deactivation radical polymerization (RDRP) and one of the more versatile methods for providing living characteri...
Keywords: Biomaterials, Living polymerization, Nanotechnology, Polymerization reactions, Radical polymerization, Reversible addition-fragmentation chain transfer polymerizations, transformation

Applying ARGET ATRP to the Growth of Polymer Brush Thin Films by Surface-initiated Polymerization

In 2006, Matyjaszewski and co-workers first described controlled radical polymerization by Activators ReGenerated by Electron Transfer Atom Transfer Radical Polymerization (ARGET ATRP),1-3 a developm...
Keywords: Antimicrobials, Ligands, Nanotubes, Oxidations, Polymerization reactions, Radical polymerization, Reductions, Reversible addition-fragmentation chain transfer polymerizations, Solution polymerization, Solvents

Concepts and Tools for RAFT Polymerization

RAFT or Reversible Addition/Fragmentation Chain Transfer is a form of living radical polymerization. RAFT polymerization was discovered at CSIRO in 1998.1 It soon became the focus of intensive resear...
Keywords: Polymerization reactions, Radical polymerization, Reversible addition-fragmentation chain transfer polymerizations

Copper(I)-mediated Living Radical Polymerization in the Presence of Pyridylmethanimine Ligands

Emergence of living radical polymerization mediated by transition metal catalysts in 1995 was a seminal piece of work in the field of synthetic polymer chemistry.1-3 Since this date, many transition ...
Keywords: Catalysis, Condensations, Evaporation, Filtration, Ligands, Oxidations, Polymer science, Polymerization reactions, Precipitation, Purification, Radical polymerization, Reductions, Solvents

Initiator/Stabilizer FAQs

In a free-radical addition polymerization, the choice of polymerization initiator depends mainly on two factors: a) its solubility and b) its decomposition temperature. If the polymerization is perfo...
Dr. S. S. Newaz
Material Matters 2006, 1.1, 3.
Keywords: Bacterial conjugations, Chromatography, Column chromatography, Emulsion polymerization, Polymerization reactions, Precipitation, Radical polymerization, Type

Tools for Performing ATRP

Controlled radical polymerization (CRP) techniques have been reviewed in a number of articles1,2 and books,3 and include nitroxide-mediated polymerization (NMP),4-7 reversible addition fragmentation ...
Keywords: Ligands, Materials Science, Polymerization reactions, Purification, Radical polymerization, Reversible addition-fragmentation chain transfer polymerizations, Solution polymerization

Typical Procedures for Polymerizing via ATRP

The following two procedures describe two ATRP polymerization reactions as performed by Prof. Dave Hadddleton′s research group at the University of Warwick.
Keywords: Gas chromatography, Ligands, Nuclear magnetic resonance spectroscopy, Polymerization reactions, Size-exclusion chromatography, Solvents

Typical Procedures for Polymerizing via RAFT

RAFT (Reversible Addition/Fragmentation Chain Transfer) is a form of living radical polymerization involving conventional free radical polymerization of a substituted monomer in the presence of a sui...
Keywords: Nuclear magnetic resonance spectroscopy, Polymerization reactions, Radical polymerization, Reversible addition-fragmentation chain transfer polymerizations

Peer-Reviewed Papers


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