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119792 Aldrich

Podocarpic acid

98%

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Properties

Related Categories Asymmetric Synthesis, Chemical Synthesis, Chiral Building Blocks, Complex Molecules
assay   98%
optical activity   [α]20/D +133°, c = 4 in ethanol
mp   193-196 °C(lit.)
Gene Information   human ... TNF(7124)

Description

Packaging

1 g in glass bottle

100 mg in glass bottle

Price and Availability

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Safety & Documentation

Safety Information

WGK Germany 
3

Protocols & Articles

Peer-Reviewed Papers

References

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Investigation of the antitumor activity of podocarpic acid derivatives. Parish EJ and Miles DH J. Pharm. Sci. 73(5), 694-6, (1984)

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Toxic effects of some conifer resin acids and tea tree oil on human epithelial and fibroblast cells. Söderberg TA, Johansson A, and Gref R Toxicology 107(2), 99-109, (1996)

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Design, synthesis and characterization of podocarpate derivatives as openers of BK channels. Cui YM, Yasutomi E, Otani Y, et al. Bioorg. Med. Chem. Lett. 18(19), 5197-200, (2008)

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Antimicrobial screening of zinc in the absence or presence of oleoresins and various resin acids. Johansson A, Sunzel B, Holm SE, et al. APMIS 103(6), 419-27, (1995)

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Inhibition of influenza virus hemagglutinin-mediated membrane fusion by a compound related to podocarpic acid. Staschke KA, Hatch SD, Tang JC, et al. Virology 248(2), 264-74, (1998)

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Design, structure activity relationships and X-Ray co-crystallography of non-steroidal LXR agonists. Bennett DJ, Carswell EL, Cooke AJ, et al. Curr. Med. Chem. 15(2), 195-209, (2008)

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Screening the foods of an endangered parrot, the kakapo (Strigops habroptilus), for oestrogenic activity using a recombinant yeast bioassay. Fidler AE, Zwart S, Pharis RP, et al. Reprod. Fertil. Dev. 12(3-4), 191-9, (2000)

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Design, synthesis, and structure-activity relationship of podocarpic acid amides as liver X receptor agonists for potential treatment of atherosclerosis. Liu W, Chen S, Dropinski J, et al. Bioorg. Med. Chem. Lett. 15(20), 4574-8, (2005)

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Discovery and development of dimeric podocarpic acid leads as potent agonists of liver X receptor with HDL cholesterol raising activity in mice and hamsters. Sheo B Singh et al Bioorg. Med. Chem. Lett. 15, 2824-8, (2005)

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Microbial transformation of podocarpic acid and evaluation of transformation products for antioxidant activity. Baraka HN Planta Med. 76(8), 815-7, (2010)

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Novel cytokine release inhibitors. Part IV: analogs of podocarpic acid. He W, Gavai A, Huang FC, et al. Bioorg. Med. Chem. Lett. 9(3), 469-74, (1999)

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Podocarpic acid as a source of an oestrogenic hormone. BRANDT CW and ROSS DJ Nature 161(4101), 892, (1948)

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Merck 14,7543

Beil. 10,326

Fieser 1,585 / Fieser 2,342 / Fieser 4,118 / Fieser 5,52 / Fieser 8,283

FT-NMR 1 (2), 1038:C / IR-Spectra (3), 948:D / IR-Spectra (2), 830:C / RegBook 1 (2), 1767:H / Structure Index 1, 282:A:5

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