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119938 Aldrich

Benzyl chloroformate

≥98%

Synonym: Carbobenzoxy chloride, Z-Chloride

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Properties

Related Categories Amine Protection, Chemical Biology, Chemical Synthesis, Other Protecting and Derivatizing Reagents, Peptide Chemistry,
vapor density   1 (vs air)
vapor pressure   1.39 psi ( 20 °C)
assay   ≥98%
refractive index   n20/D 1.519(lit.)
bp   103 °C/20 mmHg(lit.)
density   1.195 g/mL at 25 °C(lit.)
storage temp.   2-8°C

Description

Application

Cbz-protected anilines were prepared directly from aromatic carboxylic acids, sodium azide and Cbz-Cl. Also used in a recently reported 3-step synthesis of 1,2,4-oxadiazoles.

Protecting reagent in peptide synthesis.

Useful for the introduction of the benzyloxycarbonyl(Cbz,Z) protecting group

Packaging

100, 500 g in Sure/Seal™

2.5 kg in Sure/Seal™

5 g in glass bottle

Price and Availability

Safety & Documentation

Safety Information

Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1739 8 / PGI
WGK Germany 
3
Flash Point(F) 
197.6 °F
Flash Point(C) 
92 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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08168 Timestrip Plus 8 °C

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