119938 Aldrich

Benzyl chloroformate


Synonym: Carbobenzoxy chloride, Z-Chloride


Related Categories Amine Protection, Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry,
vapor density   1 (vs air)
vapor pressure   1.39 psi ( 20 °C)
assay   ≥98%
refractive index   n20/D 1.519(lit.)
bp   103 °C/20 mmHg(lit.)
density   1.195 g/mL at 25 °C(lit.)
storage temp.   2-8°C



Cbz-protected anilines were prepared directly from aromatic carboxylic acids, sodium azide and Cbz-Cl.1 Also used in a recently reported 3-step synthesis of 1,2,4-oxadiazoles.2

Protecting reagent in peptide synthesis.

Useful for the introduction of the benzyloxycarbonyl(Cbz,Z) protecting group


100, 500 g in Sure/Seal™

2.5 kg in Sure/Seal™

5 g in glass bottle

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