121967 Aldrich

Aminoacetaldehyde dimethyl acetal


Synonym: 2,2-Dimethoxyethylamine


Related Categories Acetals/Ketals/Ortho Esters, Building Blocks, Chemical Synthesis, Organic Building Blocks, Oxygen Compounds More...
assay   99%
refractive index   n20/D 1.417(lit.)
bp   135-139 °C/95 mmHg(lit.)
density   0.965 g/mL at 25 °C(lit.)



25, 100, 500 mL in glass bottle


Aminoacetaldehyde dimethyl acetal was used in a study to develop a fluorescent substrate for aldehyde dehydrogenase1. It was used in preparation of chitosan-dendrimer hybrids having various functional groups such as carboxyl, ester and poly(ethylene glycol)2. It was used in an efficient 3-step synthesis of a bicyclic proline analog from L-ascorbic acid3 and in 3-component reaction catalyzed by MgClO4 leading to α-aminophosphonates4.

General description

Aminoacetaldehyde dimethyl acetal reacts with sulfone, followed by hydrolysis and reductive amination by adding desired piperazine derivative to yield piperazine derivatives of 2-furanyl[1,2,4]triazolo[1,5-a][1,3,5]triazine5.

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