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133310 Aldrich

Aniline hydrochloride

97%

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Properties

Related Categories Amine Salts, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks More...
vapor density   4.46 (vs air)
assay   97%
mp   196-198 °C(lit.)

Description

Biochem/physiol Actions

The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.

Application

Aniline hydrochloride was used in the preparation of polyaniline coated poly(styrene-co-styrene sulfonate) nanoparticles. It was used to study the induction of Nei-like DNA glycosylases (NEIL1/2)-mediated base excision repair(BER) in rat spleen and 8-oxoguanine glycosylase 1-mediated BER due to aniline exposure.

Other Notes

This product has been replaced by A8524-ALDRICH | Aniline hydrochloride ≥99%

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Safety & Documentation

Safety Information

Signal word 
Danger
RIDADR 
UN 1548 6.1 / PGIII
WGK Germany 
3
RTECS 
CY0875000
Flash Point(F) 
381.2 °F
Flash Point(C) 
194 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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Description

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A8524 Aniline hydrochloride, ≥99%

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