|Related Categories||Amine Salts, Building Blocks, Chemical Synthesis, Nitrogen Compounds, Organic Building Blocks More...|
|vapor density||4.46 (vs air)|
The acute toxicity of aniline involves its activation in vivo to 4-hydroxyaniline and the formation of adducts with hemoglobin. In erythrocytes, this is associated with the release of iron and the accumulation of methemoglobin and the development of hemolytic anemia and inflammation of the spleen. Tumor formation is often observed in the spleen on prolonged administration.
5 g in glass bottle
Aniline hydrochloride was used in the preparation of polyaniline coated poly(styrene-co-styrene sulfonate) nanoparticles1. It was used to study the induction of Nei-like DNA glycosylases (NEIL1/2)-mediated base excision repair(BER) in rat spleen and 8-oxoguanine glycosylase 1-mediated BER due to aniline exposure2.
Certificate of Analysis
Certificate of Origin
|Symbol||GHS05, GHS06, GHS08, GHS09|
|Precautionary statements||P261-P273-P280-P301 + P310-P305 + P351 + P338-P311|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||T,N|
|Risk Statements (Europe)||23/24/25-40-41-43-48/23/24/25-50-68|
|Safety Statements (Europe)||26-27-36/37/39-45-61-63|
|RIDADR||UN 1548 6.1 / PGIII|
|Flash Point(F)||381.2 °F|
|Flash Point(C)||194 °C|
1. Preparation of PANI-coated poly (styrene-co-styrene sulfonate) nanoparticles. Kim BJ, et al. Polymer 43(1), 111-116, (2002)
Aqueous synthesis of N,S-dialkylthiophosphoramidates: design, optimisation and application to library construction and antileishmanial testing. Trmčić M, Chadbourne FL, Brear PM, et al. Org. Biomol. Chem. 11(16), 2660-75, (2013)
C(sp3)-F bond activation of CF3-substituted anilines with catalytically generated silicon cations: spectroscopic evidence for a hydride-bridged Ru-S dimer in the catalytic cycle. Stahl T, Klare HF, and Oestreich M J. Am. Chem. Soc. 135(4), 1248-51, (2013)
Organocatalytic asymmetric multicomponent reactions of aromatic aldehydes and anilines with β-ketoesters: facile and atom-economical access to chiral tetrahydropyridines. Li X, Zhao Y, Qu H, et al. Chem. Commun. 49(14), 1401-3, (2013)
Ultrafast dynamics of aniline following 269-238 nm excitation and the role of the S2(pi3s/pi sigma) state. Spesyvtsev R, Kirkby OM, and Fielding HH Faraday Discuss. 157, 165-79; discussion 243-84, (2012)
Gold-catalyzed domino cycloisomerization/Pictet-Spengler reaction of 2-(4-aminobut-1-yn-1-yl)anilines with aldehydes: synthesis of tetrahydropyrido[4,3-b]indole scaffolds. Subba Reddy BV, Swain M, Reddy SM, et al. J. Org. Chem. 77(24), 11355-61, (2012)
Ionic matrices pre-spotted matrix-assisted laser desorption/ionization plates for patient maker following in course of treatment, drug titration, and MALDI mass spectrometry imaging. Bonnel D, Franck J, Mériaux C, et al. Anal. Biochem. 434(1), 187-98, (2013)
Synthesis of N(4)-(substituted phenyl)-N(4)-alkyl/desalkyl-9H-pyrimido[4,5-b]indole-2,4-diamines and identification of new microtubule disrupting compounds that are effective against multidrug resistant cells. Gangjee A, Zaware N, Devambatla RK, et al. Bioorg. Med. Chem. 21(4), 891-902, (2013)
Synthesis, growth, crystalline perfection of 4-bromo-4'dimethylamino benzylideneaniline (BDMABA) and photons absorption of BDMABA crystal. Subashini A, Bhagavannarayana G, and Ramamurthi K Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 104, 403-8, (2013)
One-pot ring-closing metathesis/1,3-dipolar cycloaddition through assisted tandem ruthenium catalysis: synthesis of a dye with isoindolo[2,1-a]quinoline structure. Arisawa M, Fujii Y, Kato H, et al. Angew. Chem. Int. Ed. Engl. 52(3), 1003-7, (2013)
Synthesis and application of ionic liquid matrices (ILMs) for effective pathogenic bacteria analysis in matrix assisted laser desorption/ionization (MALDI-MS). Abdelhamid HN, Gopal J, and Wu HF Anal. Chim. Acta 767, 104-11, (2013)
Simulation of the chromatographic separation process in HPLC employing suspended-state NMR spectroscopy - comparison of interaction behavior for monomeric and hydride-modified C18 stationary phases. Yeman H, Nicholson T, Matyska MT, et al. J. Sep. Sci. 36(1), 173-81, (2013)
Aldrich MSDS 1, 126:A / Corp MSDS 1 (1), 270:B / FT-IR 2 (2), 2024:B / FT-IR 1 (1), 1189:B / FT-NMR 1 (2), 451:B / IR-Spectra (2), 630:B / IR-Spectra (3), 714:B / RegBook 1 (1), 1383:B / Sax 6, 360 / Sigma FT-IR 1 (2), 284:B / Structure Index 1, 214:B:1
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