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133655 Aldrich

4′-Chloroacetoacetanilide

98%

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Properties

Related Categories Amides, Building Blocks, C8 to C20+, Carbonyl Compounds, Chemical Synthesis,
InChI Key   JMRJWEJJUKUBEA-UHFFFAOYSA-N
assay   98%
mp   131-134 °C(lit.)
solubility   acetone: soluble 25 mg/mL clear, colorless to light yellow

Description

Packaging

100 g in poly bottle

Application

4′-Chloroacetoacetanilide was used in recombinant androgen receptor competitive binding assay for analysis of natural, synthetic and environmental chemicals.

General description

4′-Chloroacetoacetanilide was trilithiated with lithium diisopropylamide and condensed with several aromatic esters, followed by neutralization, separate acid cyclization and rearrangements to yield 4-anilino-6-aryl-2H-pyran-2-ones. It undergoes three-component reaction with a mixture of aromatic aldehyde and 5-aminotetrazole to form N,7-diaryl-5-methyl-4,7-dihydrotetrazolo[1,5-a]pyrimidine-6-carboxamide.

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
1
RTECS 
AK4375000

Documents

Certificate of Analysis

Protocols & Articles
Peer-Reviewed Papers
15

References

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