|Related Categories||Building Blocks, C9, Carbonyl Compounds, Chemical Synthesis, Ketones,|
|drug control||USDEA Schedule II|
|availability||available only in EU|
|density||1.003 g/mL at 20 °C(lit.)|
Phenylacetone is the immediate precursor for clandestine production of amphetamine and methamphetamine1. Phenylacetone on anaerobic incubations with rat liver mitochondria gets reduced to phenylisopropanol2.
|Precautionary statements||P301 + P310|
|Personal Protective Equipment||Eyeshields, Gloves, half-mask respirator (US), multi-purpose combination respirator cartridge (US)|
|RIDADR||UN 1993 / PGIII|
|Flash Point(F)||194 °F|
|Flash Point(C)||90 °C|
1. Comparative analysis of 1-phenyl-2-propanone (P2P), an amphetamine-type stimulant precursor, using stable isotope ratio mass spectrometry: presented in part as a poster at the 2nd meeting of the Joint European Stable Isotope User Meeting (JESIUM), Giens, France, September 2008. Schneiders S, Holdermann T, and Dahlenburg R Sci. Justice 49(2), 94-101, (2009)
Exploring the structural basis of substrate preferences in Baeyer-Villiger monooxygenases: insight from steroid monooxygenase. Franceschini S, van Beek HL, Pennetta A, et al. J. Biol. Chem. 287(27), 22626-34, (2012)
Analysis of the infrared and Raman spectra of the symmetrically substituted 1,3-diphenylurea and 1,3-diphenylacetone (dibenzyl ketone). Badawi HM and Förner W Spectrochim. Acta. A. Mol. Biomol. Spectrosc. 95, 435-41, (2012)
Blending Baeyer-Villiger monooxygenases: using a robust BVMO as a scaffold for creating chimeric enzymes with novel catalytic properties. van Beek HL, de Gonzalo G, and Fraaije MW Chem. Commun. 48(27), 3288-90, (2012)
Improvement of the biocatalytic properties of one phenylacetone monooxygenase mutant in hydrophilic organic solvents. de Gonzalo G, Rodríguez C, Rioz-Martínez A, et al. Enzyme Microb. Technol. 50(1), 43-9, (2012)
The analysis of substituted cathinones. Part 2: an investigation into the phenylacetone based isomers of 4-methylmethcathinone and N-ethylcathinone. McDermott SD, Power JD, Kavanagh P, et al. Forensic Sci. Int. 212(1-3), 13-21, (2011)
Mapping the substrate binding site of phenylacetone monooxygenase from Thermobifida fusca by mutational analysis. Dudek HM, de Gonzalo G, Pazmiño DE, et al. Appl. Environ. Microbiol. 77(16), 5730-8, (2011)
CE assay for simultaneous determination of charged and neutral impurities in dexamphetamine sulfate using a dual CD system. Wongwan S, Sungthong B, and Scriba GK Electrophoresis 31(9), 1475-81, (2010)
A Thermoanaerobacter ethanolicus secondary alcohol dehydrogenase mutant derivative highly active and stereoselective on phenylacetone and benzylacetone. Ziegelmann-Fjeld KI, Musa MM, Phillips RS, et al. Protein Eng. Des. Sel. 20(2), 47-55, (2007)
Rotational spectra and conformational structures of 1-phenyl-2-propanol, methamphetamine, and 1-phenyl-2-propanone. Tubergen MJ, Lavrich RJ, Plusquellic DF, et al. J. Phys. Chem. A 110(49), 13188-94, (2006)
Microbial degradation of illicit drugs, their precursors, and manufacturing by-products: implications for clandestine drug laboratory investigation and environmental assessment. Janusz A, Kirkbride KP, Scott TL, et al. Forensic Sci. Int. 134(1), 62-71, (2003)
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