139114 Aldrich


predominantly endo, 97%

Synonym: endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

  • CAS Number 464-45-9

  • Empirical Formula (Hill Notation) C10H18O

  • Molecular Weight 154.25

  •  Beilstein Registry Number 2038053

  •  EC Number 207-353-1

  •  MDL number MFCD00003759

  •  PubChem Substance ID 24848391

  • Popular Documents:  FTNMR (PDF)  



Related Categories Alcohols, Asymmetric Synthesis, Cell Biology, Chamaemelum nobile (Chamomile tea), Chemical Synthesis,
vapor density   5.31 (vs air)
vapor pressure   33.5 mmHg ( 25 °C)
assay   97%
optical activity   [α]20/D −35.3°, c = 5 in ethanol
bp   210 °C(lit.)
mp   206-208 °C(lit.)



100, 500 g in poly bottle

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Safety & Documentation

Safety Information

Signal word 
Hazard statements 
Precautionary statements 
UN 1312 4.1 / PGIII
WGK Germany 
Flash Point(F) 
149 °F
Flash Point(C) 
65 °C
Protocols & Articles
Peer-Reviewed Papers


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[Comparative pharmacokinetic studies of borneol in brain and plasma of stroke or sham-operated rats after administration of Xingnaojing]. Xu P, Du SY, Li Y, et al. Zhongguo Zhong Yao Za Zhi 38(21), 3763-7, (2013)


[Studies on pharmacological activity of borneol]. Xiong ZY, Xiao FM, Xu X, et al. Zhongguo Zhong Yao Za Zhi 38(6), 786-90, (2013)


[Effect of borneol on intestinal absorption of muscone in rats]. Zou L, Lin JZ, Hu HL, et al. Zhongguo Zhong Yao Za Zhi 37(22), 3490-3, (2012)


[Research of bornrol promote drugs through blood-brain barrier]. Lv X, Sun M, and Sun F Zhongguo Zhong Yao Za Zhi 37(7), 878-81, (2012)


[Effects of penetration enhancers on curcumin transdermal drug delivery]. Gao ZS, Wang L, and Zhang M Zhong Yao Cai 35(1), 141-4, (2012)


Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. Ren-Zhong W, Yan-Yan X, Yan-Ping L, et al. J. Asian Nat. Prod. Res. 14(6), 538-44, (2012)


[Volatile metabolites analysis and molecular identification of endophytic fungi bn12 from Cinnamomum camphora chvar. borneol]. Chen M, Yang L, Li Q, et al. Zhongguo Zhong Yao Za Zhi 36(23), 3217-21, (2011)


[Effect of single-used borneol and combining it with diazepam on content of neurotransmitter in corpus striatum of rats]. Zhang N, Liu P, and He X Zhongguo Zhong Yao Za Zhi 36(22), 3180-3, (2011)


[Effects of aromatic resuscitation drugs on blood brain barrier in cerebral ischemia-reperfusion injury model rats]. Ni C, Zeng N, Xu F, et al. Zhongguo Zhong Yao Za Zhi 36(18), 2562-6, (2011)


[Study on rat nasal absorption in situ of borneol based on single pass perfusion method]. Song X, Du S, Lu Y, et al. Zhongguo Zhong Yao Za Zhi 36(18), 2489-92, (2011)


[Study on pharmacokinetics of borneol in rats injected with novel-xingnaojing by GC-FID]. Lu Y, Du S, Chen X, et al. Zhongguo Zhong Yao Za Zhi 36(16), 2200-2, (2011)


Molecular cloning and functional characterization of borneol dehydrogenase from the glandular trichomes of Lavandula x intermedia. Sarker LS, Galata M, Demissie ZA, et al. Arch. Biochem. Biophys. 528(2), 163-70, (2012)


Borneol administration protects primary rat hepatocytes against exogenous oxidative DNA damage. Horváthová E, Kozics K, Srančíková A, et al. Mutagenesis 27(5), 581-8, (2012)


Natural borneol enhances geniposide ophthalmic absorption in rabbits. Song J, Bi H, Xie X, et al. Int. J. Pharm. 445(1-2), 163-70, (2013)


Fragrance material review on borneol. Bhatia SP, Letizia CS, and Api AM Food Chem. Toxicol. 46 Suppl 11, S77-80, (2008)


Treatment with cardiotonic pills(®) after ischemia-reperfusion ameliorates myocardial fibrosis in rats. Wei XH, Liu YY, Li Q, et al. Microcirculation 20(1), 17-29, (2013)


Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells. Hur J, Pak SC, Koo BS, et al. Pharm. Biol. 51(1), 30-5, (2013)


The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. Liu J, Fu S, Wei N, et al. Eur. J. Pharmacol. 688(1-3), 1-5, (2012)


Fragrance material review on l-borneol. Bhatia SP, McGinty D, Letizia CS, et al. Food Chem. Toxicol. 46 Suppl 11, S81-4, (2008)


Effect of Xiongbing compound on the pharmacokinetics and brain targeting of tetramethylpyrazine. Wang LS, Shi ZF, Zhang YF, et al. J. Pharm. Pharmacol. 64(11), 1688-94, (2012)


Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol. Su J, Chen J, Li L, et al. J. Food Sci. 77(6), C658-64, (2012)


Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations. Zhao JY, Lu Y, Du SY, et al. J. Zhejiang Univ. Sci. B 13(12), 990-6, (2012)


Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). Ceacero-Vega AA, Ballesteros B, Bejan I, et al. J. Phys. Chem. A 116(16), 4097-107, (2012)


Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse. Su J, Chen J, Li L, et al. Chem. Pharm. Bull. 60(6), 736-42, (2012)


RAPD and phytochemical analysis of Thymus moroderi plantlets after cryopreservation. Marco-Medina A and Casas JL Cryo. Letters 34(2), 119-27, (2013)


Velamo do campo: its volatile constituents, secretory elements, and biological activity. El Babili F, Roques C, Haddioui L, et al. J. Med. Food 15(7), 671-6, (2012)


The effect of camphor and borneol on rat thymocyte viability and oxidative stress. Cherneva E, Pavlovic V, Smelcerovic A, et al. Molecules 17(9), 10258-66, (2012)


In situ and in vivo study of nasal absorption of borneol in rats. Song X, Lu Y, Wen R, et al. Pharmazie 67(10), 848-51, (2012)


Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. Zhang R, Mi SQ, and Wang NS Eur. J. Drug Metab. Pharmacokinet. 38(3), 159-69, (2013)


Merck 14,1338

Beil. 6,III,297

Aldrich MSDS 1, 217:A / Corp MSDS 1 (1), 478:D / FT-IR 1 (1), 169:B / FT-IR 2 (1), 236:B / FT-NMR 1 (1), 251:A / IR-Spectra (3), 101:G / IR-Spectra (2), 94:H / NMR-Reference 2 (1), 154:C / RegBook 1 (1), 167:G / Sax 6, 1989 / Sigma FT-IR 1 (2), 328:A / Structure Index 1, 21:B:7 / Vapor Phase 3, 246:A

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