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139114 Aldrich

(−)-Borneol

predominantly endo, 97%

Synonym: endo-(1S)-1,7,7-Trimethylbicyclo[2.2.1]heptan-2-ol

  • CAS Number 464-45-9

  • Empirical Formula (Hill Notation) C10H18O

  • Molecular Weight 154.25

  •  Beilstein Registry Number 2038053

  •  EC Number 207-353-1

  •  MDL number MFCD00003759

  •  PubChem Substance ID 24848391

  • Popular Documents:  FTNMR (PDF)  

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Properties

Related Categories Alcohols, Asymmetric Synthesis, Cell Biology, Chamaemelum nobile (Chamomile tea), Chemical Synthesis,
vapor density   5.31 (vs air)
vapor pressure   33.5 mmHg ( 25 °C)
assay   97%
optical activity   [α]20/D −35.3°, c = 5 in ethanol
bp   210 °C(lit.)
mp   206-208 °C(lit.)

Description

Packaging

100, 500 g in poly bottle

Price and Availability

Suggested Laboratory Gloves


Laboratory GlovesThis substance has been tested against several types of hand protection for CE compliance. Click below to find the recommended gloves for handling this product.



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Safety & Documentation

Safety Information

Symbol 
Signal word 
Warning
Hazard statements 
Precautionary statements 
Hazard Codes (Europe) 
Risk Statements (Europe) 
Safety Statements (Europe) 
16-36/37
RIDADR 
UN 1312 4.1 / PGIII
WGK Germany 
2
RTECS 
DT5095000
Flash Point(F) 
149 °F
Flash Point(C) 
65 °C

Protocols & Articles

Peer-Reviewed Papers

References

Set your institution to view full text papers.

Treatment with cardiotonic pills(®) after ischemia-reperfusion ameliorates myocardial fibrosis in rats. Wei XH, Liu YY, Li Q, et al. Microcirculation 20(1), 17-29, (2013)

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Molecular cloning and functional characterization of borneol dehydrogenase from the glandular trichomes of Lavandula x intermedia. Sarker LS, Galata M, Demissie ZA, et al. Arch. Biochem. Biophys. 528(2), 163-70, (2012)

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[Comparative pharmacokinetic studies of borneol in brain and plasma of stroke or sham-operated rats after administration of Xingnaojing]. Xu P, Du SY, Li Y, et al. Zhongguo Zhong Yao Za Zhi 38(21), 3763-7, (2013)

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[Studies on pharmacological activity of borneol]. Xiong ZY, Xiao FM, Xu X, et al. Zhongguo Zhong Yao Za Zhi 38(6), 786-90, (2013)

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[Effect of borneol on intestinal absorption of muscone in rats]. Zou L, Lin JZ, Hu HL, et al. Zhongguo Zhong Yao Za Zhi 37(22), 3490-3, (2012)

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[Research of bornrol promote drugs through blood-brain barrier]. Lv X, Sun M, and Sun F Zhongguo Zhong Yao Za Zhi 37(7), 878-81, (2012)

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[Effects of penetration enhancers on curcumin transdermal drug delivery]. Gao ZS, Wang L, and Zhang M Zhong Yao Cai 35(1), 141-4, (2012)

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Enhancing effects of different dosages of borneol on pharmacokinetics of salvanic acid B after oral administration to rats. Ren-Zhong W, Yan-Yan X, Yan-Ping L, et al. J. Asian Nat. Prod. Res. 14(6), 538-44, (2012)

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[Volatile metabolites analysis and molecular identification of endophytic fungi bn12 from Cinnamomum camphora chvar. borneol]. Chen M, Yang L, Li Q, et al. Zhongguo Zhong Yao Za Zhi 36(23), 3217-21, (2011)

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[Effect of single-used borneol and combining it with diazepam on content of neurotransmitter in corpus striatum of rats]. Zhang N, Liu P, and He X Zhongguo Zhong Yao Za Zhi 36(22), 3180-3, (2011)

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[Effects of aromatic resuscitation drugs on blood brain barrier in cerebral ischemia-reperfusion injury model rats]. Ni C, Zeng N, Xu F, et al. Zhongguo Zhong Yao Za Zhi 36(18), 2562-6, (2011)

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[Study on rat nasal absorption in situ of borneol based on single pass perfusion method]. Song X, Du S, Lu Y, et al. Zhongguo Zhong Yao Za Zhi 36(18), 2489-92, (2011)

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The effects of combined menthol and borneol on fluconazole permeation through the cornea ex vivo. Liu J, Fu S, Wei N, et al. Eur. J. Pharmacol. 688(1-3), 1-5, (2012)

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[Study on pharmacokinetics of borneol in rats injected with novel-xingnaojing by GC-FID]. Lu Y, Du S, Chen X, et al. Zhongguo Zhong Yao Za Zhi 36(16), 2200-2, (2011)

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Natural borneol enhances geniposide ophthalmic absorption in rabbits. Song J, Bi H, Xie X, et al. Int. J. Pharm. 445(1-2), 163-70, (2013)

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Borneol administration protects primary rat hepatocytes against exogenous oxidative DNA damage. Horváthová E, Kozics K, Srančíková A, et al. Mutagenesis 27(5), 581-8, (2012)

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Fragrance material review on borneol. Bhatia SP, Letizia CS, and Api AM Food Chem. Toxicol. 46 Suppl 11, S77-80, (2008)

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Borneol alleviates oxidative stress via upregulation of Nrf2 and Bcl-2 in SH-SY5Y cells. Hur J, Pak SC, Koo BS, et al. Pharm. Biol. 51(1), 30-5, (2013)

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Fragrance material review on l-borneol. Bhatia SP, McGinty D, Letizia CS, et al. Food Chem. Toxicol. 46 Suppl 11, S81-4, (2008)

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Effect of Xiongbing compound on the pharmacokinetics and brain targeting of tetramethylpyrazine. Wang LS, Shi ZF, Zhang YF, et al. J. Pharm. Pharmacol. 64(11), 1688-94, (2012)

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Preparation of natural borneol/2-hydroxypropyl-β-cyclodextrin inclusion complex and its effect on the absorption of tetramethylpyrazine phosphate in mouse. Su J, Chen J, Li L, et al. Chem. Pharm. Bull. 60(6), 736-42, (2012)

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Comparative pharmacokinetic studies of borneol in mouse plasma and brain by different administrations. Zhao JY, Lu Y, Du SY, et al. J. Zhejiang Univ. Sci. B 13(12), 990-6, (2012)

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Formation of β-cyclodextrin inclusion enhances the stability and aqueous solubility of natural borneol. Su J, Chen J, Li L, et al. J. Food Sci. 77(6), C658-64, (2012)

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Kinetics and mechanisms of the tropospheric reactions of menthol, borneol, fenchol, camphor, and fenchone with hydroxyl radicals (OH) and chlorine atoms (Cl). Ceacero-Vega AA, Ballesteros B, Bejan I, et al. J. Phys. Chem. A 116(16), 4097-107, (2012)

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The effect of camphor and borneol on rat thymocyte viability and oxidative stress. Cherneva E, Pavlovic V, Smelcerovic A, et al. Molecules 17(9), 10258-66, (2012)

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Velamo do campo: its volatile constituents, secretory elements, and biological activity. El Babili F, Roques C, Haddioui L, et al. J. Med. Food 15(7), 671-6, (2012)

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Effect of borneol on cytochrome P450 3A enzyme and midazolam pharmacokinetics in rats. Zhang R, Mi SQ, and Wang NS Eur. J. Drug Metab. Pharmacokinet. 38(3), 159-69, (2013)

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In situ and in vivo study of nasal absorption of borneol in rats. Song X, Lu Y, Wen R, et al. Pharmazie 67(10), 848-51, (2012)

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RAPD and phytochemical analysis of Thymus moroderi plantlets after cryopreservation. Marco-Medina A and Casas JL Cryo. Letters 34(2), 119-27, (2013)

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Merck 14,1338

Beil. 6,III,297

Aldrich MSDS 1, 217:A / Corp MSDS 1 (1), 478:D / FT-IR 1 (1), 169:B / FT-IR 2 (1), 236:B / FT-NMR 1 (1), 251:A / IR-Spectra (3), 101:G / IR-Spectra (2), 94:H / NMR-Reference 2 (1), 154:C / RegBook 1 (1), 167:G / Sax 6, 1989 / Sigma FT-IR 1 (2), 328:A / Structure Index 1, 21:B:7 / Vapor Phase 3, 246:A

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