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145289 Aldrich

4-Chloro-2-methylthiopyrimidine

98%

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Properties

Related Categories Building Blocks, C4 to C5, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks,
InChI Key   DFOHHQRGDOQMKG-UHFFFAOYSA-N
assay   98%
refractive index   n20/D 1.6(lit.)
bp   139-140 °C/36 mmHg(lit.)
mp   −2 °C(lit.)
density   1.381 g/mL at 25 °C(lit.)

Description

Packaging

10, 50 g in glass bottle

Application

4-Chloro-2-methylthiopyrimidine was used in the total synthesis of the marine alkaloid variolin B1 and 2-hydroxy-4-pyrimidinecarboxylic acid. It was used in the synthesis of 2,4-disubstituted pyrimidines, a novel class of KDR kinase inhibitors. It was used as building block in medicinal chemistry synthesis.

Price and Availability

Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 1760 8 / PGII
WGK Germany 
3
Flash Point(F) 
235.4 °F
Flash Point(C) 
113 °C
Protocols & Articles
Peer-Reviewed Papers
15

References

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