151882 Aldrich

Deuterium oxide

99.9 atom % D

Synonym: Heavy water, Water-d2



Related Categories Alphabetical Listings, Biomolecular NMR, D, Deuterium oxide, Minimal Media Components,
isotopic purity   99.9 atom % D
refractive index   n20/D 1.328(lit.)
bp   101.4 °C(lit.)
mp   3.8 °C(lit.)
density   1.107 g/mL at 25 °C(lit.)


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1 L in glass bottle

1, 1.107, 4 kg in glass bottle

10×0.6, 10×0.75, 10×1 mL in ampule

10, 25, 100, 250, 500 g in glass bottle


Deuterium oxide (Heavy water, Water-d2, D2O) has been used as solvent for the dissolution of internal standard and sample during quantification experiments by NMR. It has been used for the dissolution of tris(2,2′-bipyridyl)dichlororuthenium(II) hexahydrate Ru(bpy)3.4

General description

Deuterium oxide, a deuterated solvent, is a standard prurity solvent for NMR (Nuclear Magnetic Resonance) analyses. Various thermodynamic properties (such as intermolecular vibrational frequencies, energy of the hydrogen bond, free energy, enthalpy and entropy) of liquid deuterium oxide have been evaluated. Ionization constant for D2O (in the range of 5-50°C), pK values (at 25°C) and enthalpy, entropy, heat capacity change (for the dissociation of D2O) have been reported.

Price and Availability

Suggested Laboratory Gloves

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Safety & Documentation

Safety Information

NONH for all modes of transport
WGK Germany 
Protocols & Articles


Isotopic Labeling in Solid-state NMR of Proteins

ISOTEC Stable Isotopes: Resonating with the Advancing Field of Biomolecular NMR (1.21 Mb PDF)
Francesca M. Marassi, Ph.D.
ISOTEC® Stable Isotopes: Resonating with the Advancing Field of Biomolecular NMR, 2–3
Keywords: Asymmetric synthesis, Molecular biology, Nuclear magnetic resonance spectroscopy, Spectroscopy

Solid-state NMR on Larger Biomolecules

In the last years, remarkable progress has been made to probe molecular structure of biological systems using Magic Angle Spinning solid-state NMR (ssNMR). Prominent examples relate to research areas...
Marc Baldus
ISOTEC® Stable Isotopes: Products for Solid State NMR, 2010, 2–4
Keywords: Atomic absorption spectroscopy, Biochemistry, Biological processes, Catalysis, Cell biology, Gene expression, Mass spectrometry, Materials Science, Microscopy, Molecular biology, Nuclear magnetic resonance spectroscopy, Photosynthesis, Polymorphisms, Reductions, Research areas, Sample preparations, Scanning electron microscopy

Peer-Reviewed Papers


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