• USA Home
  • 157260 - 1-Hydroxybenzotriazole hydrate

157260 Aldrich

1-Hydroxybenzotriazole hydrate

wetted with not less than 14 wt. % water, 97%

Synonym: HOBt Hydrate



Related Categories Active Esters/Additives, Chemical Biology, Chemical Synthesis, Coupling, Peptide Chemistry,
assay   97%
quality   synthesis grade
mp   155-158 °C(lit.)


Frequently Asked Questions

Frequently Asked Questions are available for this Product.


Additive used in oligonucleotide couplings and in racemization-free peptide couplings.


25, 100, 250 g in glass bottle

Price and Availability

Cross-Coupling Guide
Safety & Documentation

Safety Information

GHS02  GHS02
Signal word 
Hazard statements 
Precautionary statements 
Supplemental Hazard Statements 
Explosive when dry., Risk of explosion if heated under confinement.
UN3474 - class 4.1 - PG 1 - 1-Hydroxybenzotriazole, monohydrate
WGK Germany 

Frequently Asked Questions

Which document(s) contains shelf-life or expiration date information for a given product?
If available for a given product, the recommended re-test date or the expiration date can be found on the Certificate of Analysis. These documents are located on the product detail page under Useful Links & Tools. Click on the following link to search for a Certificate of Analysis. Please click the following link to see the details on our Product Dating Information.
How do I get lot-specific information or a Certificate of Analysis?
A Certificate of Analysis is available by lot number and can be obtained through our Advanced Search Option: http://www.sigmaaldrich.com/catalog/AdvancedSearchPage.do
How do I find price and availability?
There are several ways to find pricing and availability for our products.  Once you log onto our website, you will find the price and availability displayed on the product detail page. You can contact any of our Customer Sales and Service offices to receive a quote.  USA customers:  1-800-325-3010 or view local office numbers. 
What is the Department of Transportation shipping information for this product?
Transportation information can be found in Section 14 of the product's (M)SDS. To access the shipping information for this material, use the link on the product detail page for the product, or search here. 
Why is Product 157260, Hydroxybenzotriazole hydrate wet?
Hydroxybenzotriazole hydrate is a solid that is explosive when dry. Our specification for this product is >14% water.
Can Product 157260, Hydroxybenzotriazole hydrate, be dried?
Drying hydroxybenzotriazole hydrate should not be attempted because of its explosive nature.
How is Product 157260, Hydroxybenzotriazole hydrate, shipped?
Hydroxybenzotriazole hydrate can not travel be sea or air. It is typically shipped by truck.
My question is not addressed here, how can I contact Technical Service for assistance?
Use the option to the right to "Ask a Question" by email of a Technical Service Scientist.
Show more questions
Protocols & Articles

Related Content

Indoles, Purines, and Their Isosteres

Substituted indoles and purines have frequently been referred to as “privileged structures” since they are capable of binding to multiple receptors with high affinity, and thus have applications acro...
Keywords: Building blocks, Medicinal chemistry

Peer-Reviewed Papers


Related Products

related product

Product #


Add to Cart

711489 1-Hydroxybenzotriazole hydrate, wetted with not less than 20 wt. % water, 97%

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?