|Related Categories||Amine Protection, Chemical Biology, Chemical Synthesis, Others, Peptide Chemistry,|
Amino acid derivatizing agent for HLPC analysis.1 N-protecting reagent for peptide2 and oligonucleotide3 syntheses.
Reagent for amino group protection recently used in the synthesis of a bicyclic proline analog.
Reagent for derivatizing amino acids for HPLC amino acid analysis and for preparing N-Fmoc amino acids for solid-phase peptide synthesis.
1, 5, 25 g in glass bottle
Certificate of Analysis
|Precautionary statements||P280-P305 + P351 + P338-P310|
|Personal Protective Equipment||Eyeshields, Faceshields, full-face particle respirator type N100 (US), Gloves, respirator cartridge type N100 (US), type P1 (EN143) respirator filter, type P3 (EN 143) respirator cartridges|
|Hazard Codes (Europe)||C|
|Risk Statements (Europe)||34|
|Safety Statements (Europe)||26-36/37/39-45|
|RIDADR||UN 3261 8 / PGII|
2. J. Chem. Soc. Chem. Commun., 369, (1993)
3. Helv. Chim. Acta 75, 1111, (1992)
Synthesis, 3122, (2006)
Applicability of LC-MS/MS to optimize derivatization of topiramate with FMOC-Cl using reacted/intact drug ratio. Mohammadi B, Tammari E, Fakhri S, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 928, 32-6, (2013)
9-fluorenylmethyl chloroformate as a fluorescence-labeling reagent for derivatization of carboxylic acid moiety of sodium valproate using liquid chromatography/tandem mass spectrometry for binding characterization: a human pharmacokinetic study. Mohammadi B, Majnooni MB, Khatabi PM, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 880(1), 12-8, (2012)
Determination of biogenic amines in infusions of tea (Camellia sinensis) by HPLC after derivatization with 9-fluorenylmethoxycarbonyl chloride (Fmoc-Cl). Brückner H, Flassig S, and Kirschbaum J Amino Acids 42(2-3), 877-85, (2012)
High-performance liquid chromatographic determination of memantine hydrochloride in rat plasma using sensitive fluorometric derivatization. Xie MF, Zhou W, Tong XY, et al. J. Sep. Sci. 34(3), 241-6, (2011)
Residue determination of glyphosate in environmental water samples with high-performance liquid chromatography and UV detection after derivatization with 4-chloro-3,5-dinitrobenzotrifluoride. Qian K, Tang T, Shi T, et al. Anal. Chim. Acta 635(2), 222-6, (2009)
Amino acid analysis by high-performance liquid chromatography after derivatization with 9-fluorenylmethyloxycarbonyl chloride Literature overview and further study. Jámbor A, Molnár-Perl I. J. Chromatogr. A. 1216, 3064-3077, (2009)
Comparison of different amino acid derivatives and analysis of rat brain microdialysates by liquid chromatography tandem mass spectrometry. Uutela P, Ketola RA, Piepponen P, et al. Anal. Chim. Acta 633(2), 223-31, (2009)
Capillary electrophoresis-electrospray ionization mass spectrometry for rapid and sensitive N-glycan analysis of glycoproteins as 9-fluorenylmethyl derivatives. Nakano M, Higo D, Arai E, et al. Glycobiology 19(2), 135-43, (2009)
A fluorometric high-performance liquid chromatography procedure for simultaneous determination of methylamine and aminoacetone in blood and tissues. Xiao S and Yu PH Anal. Biochem. 384(1), 20-6, (2009)
Development and validation of a reversed-phase high-performance liquid chromatography assay for polymyxin B in human plasma. Cao G, Ali FE, Chiu F, et al. J. Antimicrob. Chemother. 62(5), 1009-14, (2008)
Simultaneous analysis of amino acids and amines as their o-phthalaldehyde-ethanethiol-9-fluorenylmethyl chloroformate derivatives in cheese by high-performance liquid chromatography. Korös A, Varga Z, and Molnár-Perl I J. Chromatogr. A 1203(2), 146-52, (2008)
Development and validation of a liquid chromatography-fluorescence-mass spectrometry method to measure glyphosate and aminomethylphosphonic acid in rat plasma. Bernal J, Bernal JL, Martin MT, et al. J. Chromatogr. B. Analyt. Technol. Biomed. Life Sci. 878(31), 3290-6, (2010)
Analysis of synephrine in da-cheng-qi decoction by HPLC employing precolumn derivatization with 9-fluorenylmethyl chloroformate. Liu Y, Xu F, Zhang Z, et al. J. Chromatogr. Sci. 47(10), 925-30, (2009)
Generation of a natural glycan microarray using 9-fluorenylmethyl chloroformate (FmocCl) as a cleavable fluorescent tag. Song X, Lasanajak Y, Rivera-Marrero C, et al. Anal. Biochem. 395(2), 151-60, (2009)
Determination of myriocin in natural and cultured Cordyceps cicadae using 9-fluorenylmethyl chloroformate derivatization and high-performance liquid chromatography with UV-detection. Yu J, Xu H, Mo Z, et al. Anal. Sci. 25(7), 855-9, (2009)
Influence of complexation phenomena with multivalent cations on the analysis of glyphosate and aminomethyl phosphonic acid in water. Freuze I, Jadas-Hecart A, Royer A, et al. J. Chromatogr. A 1175(2), 197-206, (2007)
Determination of sulphonamides in animal tissues by high performance liquid chromatography with pre-column derivatization of 9-fluorenylmethyl chloroformate. Zou QH, Xie MX, Wang XF, et al. J. Sep. Sci. 30(16), 2647-55, (2007)
Caprino, L.A. and Han. G.Y. J. Org. Chem. 37, 3404, (1972)
L.A. Carpino Acc. Chem. Res. 20, 401, (1987)
The flouren-9-ylmethoxycarbonyl group for the protection of hydroxy-groups; its application in the synthesis of an octathymidylic acid fragment. Gioeli, C. and Chattopadhyaya, J.B. J. Chem. Soc. Chem. Commun., 672, (1982)
Synthesis of phosphate-methylated DNA fragments using 9-fluorenylmethoxycarbonyl as transient base protecting group. Koole, L.H J. Org. Chem. 54, 1657, (1989)
Fieser 3,145 / Fieser 4,237
Aldrich MSDS 1, 948:B / Corp MSDS 1 (1), 1688:B / FT-IR 1 (2), 339:C / FT-IR 2 (2), 2938:A / FT-NMR 1 (2), 1336:B / IR-Spectra (2), 924:H / IR-Spectra (3), 1057:B / NMR-Reference 2 (2), 332:D / RegBook 1 (2), 1967:G / Sigma FT-IR 1 (2), 562:D / Structure Index 1, 316:C:4
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