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161462 Aldrich

N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride (EDC) 98%

≥98%

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Properties

assay   ≥98%
mp   111-113 °C(lit.)

Description

Application

Coupling reagent used to form amide bonds1 in oligonucleotides2 and tetraazamacrocycles.3

Water soluble carbodiimide for the preparation of chloroanthraquinone hydrazides, which unexpectedly cyclize to anthrapyrazoles (en route to developing histochemical probes).

Other Notes

This product has been replaced by E7750-Sigma-Aldrich | N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride commercial grade, powder

Price and Availability

Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Precautionary statements 
Personal Protective Equipment 
Hazard Codes (Europe) 
Xi
Risk Statements (Europe) 
Safety Statements (Europe) 
26-36/37/39
WGK Germany 
3
RTECS 
FF2200000

Protocols & Articles

Peer-Reviewed Papers

References

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1. Tetrahedron Lett. 34, 7685, (1993)

2. Tetrahedron Lett. 34, 6189, (1993)

3. Convenient synthesis of bifunctional tetraaza macrocycles. Bioconjug. Chem. 3, 108, (1992)

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Tetrahedron Lett. 45, 4977-4980, (2004)

Merck 14,10328

Aldrich MSDS 1, 749:C / Corp MSDS 1 (1), 1344:A / FT-IR 1 (1), 877:A / FT-IR 2 (1), 1486:A / IR-Spectra (2), 465:B / IR-Spectra (3), 524:E / NMR-Reference 2 (1), 729:B / RegBook 1 (1), 1035:F / Sax 6, 1127 / Sigma FT-IR 1 (2), 546:C / Structure Index 1, 160:C:8

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E7750 N-(3-Dimethylaminopropyl)-N′-ethylcarbodiimide hydrochloride, commercial grade, powder

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