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162434 Aldrich

4-Chloro-2-phenylquinazoline

97%

Synonym: AM-ex-OL®, NSC 400965

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Properties

Related Categories Building Blocks, Chemical Synthesis, Halogenated Heterocycles, Heterocyclic Building Blocks, Quinazolines More...
InChI Key   OBHKONRNYCDRKM-UHFFFAOYSA-N
assay   97%
mp   124-126 °C(lit.)

Description

Packaging

5 g in glass bottle

Application

4-Chloro-2-phenylquinazoline was used in synthesis of axially chiral quinazoline-containing phosphinamine ligand, N,N,2-triphenylquinazolin-4-amine, sulfanyl and sulfinylbenzodiazines. It was used as reagent for the conversion of phenols to anilines.

Reactant involved in the synthesis of biologically active molecules including:
• Nitrotriazole amines or nitroimidazole amines for use as antitrypanosomal activity and mammalian cytotoxicity
• Quinazoline-containing piperazinylpyrimidine derivatives with antitumor activity
• Quinazoline substituted cyclopentane as HCV NS3/4A protease inhibitors
• Quinazolines with antibacterial and antitumor activity
• Aurora inhibitor MK-0457

Reactant involved in Suzuki-Miyaura cross-coupling and catalyst-free / base-free water promoted nucleophilic aromatic substitution

Legal Information

AM-ex-OL is a registered trademark of Sigma-Aldrich Co. LLC

Price and Availability

Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles
Peer-Reviewed Papers
15

References

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