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16490 Aldrich

Bromopyruvic acid

≥97.0% (T)

Synonym: 3-Bromo-2-oxopropionic acid

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Properties

Related Categories Aerobic Glycolysis (the Warburg Effect), Building Blocks, C1 to C5, Cancer Metabolism, Cancer Research,
InChI Key   PRRZDZJYSJLDBS-UHFFFAOYSA-N
assay   ≥97.0% (T)
mp   77-82 °C
solubility   water: soluble1 g/10 mL, clear, colorless
storage temp.   2-8°C

Description

Other Notes

Affinity label for cysteine residues; Cross-linker between nucleic acids and proteins

Packaging

10, 50, 500 g in glass bottle

Application

Bromopyruvic acid was used in the synthesis of imidazo[1,2-a]pyridine-2-carboxylic acids.

General description

Bromopyruvic acid is an affinity label for cysteine residues†. It acts as cross-linker between nucleic acids and proteins. Kinetics of inactivation of pancreatic ribonuclease A by bromopyruvic acid has been investigated.

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Safety & Documentation

Safety Information

Symbol 
GHS05  GHS05
Signal word 
Danger
Hazard statements 
Precautionary statements 
RIDADR 
UN 3261 8 / PGII
WGK Germany 
3
RTECS 
UZ0840000
Protocols & Articles

Articles

Aerobic Glycolysis and the Warburg Effect

The Warburg effect is the enhanced conversion of glucose to lactate observed in tumor cells, even in the presence of normal levels of oxygen. Otto Heinrich Warburg demonstrated in 1924 that cancer ce...
Keywords: Aerobic, Biofiles, Cancer, Cell proliferation, Clinical, Glycolysis, PAGE, Phosphorylations, Support, Transcription

Peer-Reviewed Papers
15

References

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