• USA Home
  • 171565 - Phenylmagnesium bromide solution

EMAIL THIS PAGE TO A FRIEND
171565 Aldrich

Phenylmagnesium bromide solution

3.0 M in diethyl ether

Purchase

Properties

Related Categories Aryl, Chemical Synthesis, Grignard Reagents, Organometallic Reagents
InChI Key   ANRQGKOBLBYXFM-UHFFFAOYSA-M
concentration   3.0 M in diethyl ether
density   1.134 g/mL at 25 °C

Description

Other Notes

Storage below 25°C may cause formation of crystalline magnesium salts. Moving container to a warm location and occasional gentle swirling should redissolve the solid

Packaging

18 L in Kilo-Lab™

50, 100, 800 mL in Sure/Seal™

View returnable container options.

Application

Phenylmagnesium bromide was used for the synthesis of end-functionalized regioregular poly(3-alkylthiophene)s. It was also used for the monoalkylation of aliphatic primary amine to generate secondary amines by the Grignard reaction of 1-[(alkylamino) methyl] benzotriazoles.
It may be used for synthesis of the following:
• 1,3,3-trimethyl-6-phenyl-2-oxabicyclo[2.2.2]octan-6-ol
•  6-benzyl-1,3,3-trimethyl-2-oxabicyclo[2.2.2]octan-6-ol
• (3-(2-Dithiobenzoatepropionyl)propyl)dimethylmethoxysilane, reversible addition-fragmentation chain transfer polymerization (RAFT)-silane agent
• series of o-substituted benzophenones

General description

Phenylmagnesium bromide solution contains 3M phenylmagnesium bromide in diethyl ether. It can act as a strong acid and Lewis acid. It can undergo addition reaction with many unsaturated functional groups. The phenyl group can displace halide from other organic compounds. Phenylmagnesium bromide is a Grignard reagent. Reaction of β-cyclohexanedione (dihydroresorcinol) with phenylmagnesium bromide has been investigated.

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

Symbol 
Signal word 
Danger
Hazard statements 
Supplemental Hazard Statements 
May form explosive peroxides., Reacts violently with water.
RIDADR 
UN 3399A 4.3(3) / PGI
WGK Germany 
3
Flash Point(F) 
-40 °F
Flash Point(C) 
-40 °C

Documents

Certificate of Analysis

Certificate of Origin

Protocols & Articles

Articles

Reagents for C–C Bond Formation

Aldrich carries a large variety of electrophiles and nucleophiles that are widely used in C–C bond-forming reactions. This group of products contains many organometallic reagents as well as commonly-...
ChemFiles Volume 1 Article 3
Keywords: Acylations, Alkylations

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?