EMAIL THIS PAGE TO A FRIEND
17249 Aldrich

α-Methyl-L-proline

≥98.0% (TLC)

  • CAS Number 42856-71-3

  • Empirical Formula (Hill Notation) C6H11NO2

  • Molecular Weight 129.16

  •  Beilstein Registry Number 4350211

  •  MDL number MFCD01318647

  •  PubChem Substance ID 57647622

Purchase

Properties

Related Categories Chemical Biology, Chemical Synthesis, Peptide Chemistry, Proline Derivatives, Unnatural Amino Acids & Derivatives More...
InChI Key   LWHHAVWYGIBIEU-LURJTMIESA-N
assay   ≥98.0% (TLC)

Description

Packaging

1 g in poly bottle

250 mg in poly bottle

Price and Availability


Cross-Coupling Guide
Safety & Documentation

Safety Information

RIDADR 
NONH for all modes of transport
WGK Germany 
3
Protocols & Articles

Articles

Proline Analogs

The first examples were reported in the mid-70s, when L-proline was applied to Robinson annulation reactions. However, the big potential of proline as an organocatalyst was discovered at the beginnin...
Aldrich ChemFiles 2007, 7.9, 3.
Keywords: Aldol condensation, Aldol reaction, Alkylations, Aminations, Annulations, Asymmetric synthesis, Building blocks, Catalysis, Chemfiles, Condensations, Cyclopropanations, Help, Mannich Reaction, Methods, Michael Addition, Organocatalysis, Robinson Annulation, transformation

Proline Analogs

Coined by Jacobsen1 as the “simplest enzyme,” L-proline is capable of effecting a variety of catalytic asymmetric transformations. The first examples were reported in the mid-70s, when L-proline was ...
Aldrich ChemFiles 2006, 6.4, 3.
Keywords: Aldol reaction, Alkylations, Aminations, Annulations, Asymmetric synthesis, Catalysis, Chemfiles, Cyclopropanations, Drug discovery, Epoxidations, Help, Mannich Reaction, Methods, Michael Addition, Robinson Annulation, Tools, transformation

Proline Derivatives and Analogs

Proline is a non-polar proteinogenic amino acid that forms a tertiary amide when incorporated into peptides. It does not have a hydrogen on the amide group and therefore cannot act as a hydrogen bond...
Chemfiles Volume 5 Article 12
Keywords: Adhesion, Biochemistry, Catalysis, Deposition, Hydroxylations, Isomerizations, Nucleic acid hybridization, Pharmaceutical, Reductions, Substitutions, Type

Proline Derivatives

Proline is a non-polar, natural amino acid that forms a tertiary amide when incorporated into peptides. Thus, it is the only proteinogenic amino acid that does not act as a hydrogen bond donor in a p...
Matthias Junkers
Aldrich ChemFiles 2008, 8.7, 8.
Keywords: Asymmetric synthesis, Chemfiles, Pharmaceutical

Peer-Reviewed Papers
15

References

Set your institution to view full text papers.
Related Products

Technical Service:

Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

Bulk Ordering & Pricing:

Need larger quantities for your development, manufacturing or research applications?